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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3M2
All Species:
39.39
Human Site:
Y60
Identified Species:
61.9
UniProt:
P53677
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53677
NP_001127768.1
418
46977
Y60
H
H
Y
L
L
S
V
Y
R
H
K
I
F
F
V
Chimpanzee
Pan troglodytes
XP_001141331
436
49226
Y60
H
H
Y
L
L
S
V
Y
R
H
K
I
F
F
V
Rhesus Macaque
Macaca mulatta
XP_001098843
418
46925
Y60
H
H
Y
L
I
S
I
Y
R
D
K
L
F
F
V
Dog
Lupus familis
XP_539956
418
46980
Y60
H
H
Y
L
L
S
V
Y
R
H
K
I
F
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2R9
418
46898
Y60
H
H
Y
L
L
S
V
Y
R
H
K
I
F
F
V
Rat
Rattus norvegicus
P53678
418
46856
Y60
H
H
Y
L
L
S
V
Y
R
H
K
I
F
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509676
418
46941
Y60
H
H
Y
L
L
S
V
Y
R
H
K
I
F
F
V
Chicken
Gallus gallus
Q5ZMP7
418
46954
Y60
L
H
Y
L
I
S
I
Y
R
D
K
I
F
F
V
Frog
Xenopus laevis
Q801Q8
435
49666
R60
T
S
F
F
H
V
K
R
S
N
I
W
L
A
A
Zebra Danio
Brachydanio rerio
Q6NWK2
436
49641
R60
T
S
F
F
H
V
K
R
S
N
I
W
L
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788873
415
46777
D60
Y
L
I
T
V
Q
R
D
T
V
S
L
V
A
A
Honey Bee
Apis mellifera
XP_624899
417
47249
Y60
H
H
Y
L
I
S
I
Y
R
C
N
M
F
F
V
Nematode Worm
Caenorhab. elegans
P35602
422
48210
K61
D
T
N
F
V
F
I
K
H
T
N
I
Y
L
V
Sea Urchin
Strong. purpuratus
XP_788000
416
46931
Y60
H
H
Y
L
I
S
I
Y
R
N
Q
I
Y
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
I60
N
G
L
E
Y
L
F
I
Q
H
N
D
L
Y
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
83.9
99.5
N.A.
98.3
98.3
N.A.
98.8
83
26.2
26.1
N.A.
69.8
72
27.2
77.5
Protein Similarity:
100
95.8
94.5
99.5
N.A.
99.2
99.2
N.A.
99.2
93.7
47.8
47.4
N.A.
85.6
86.8
50.4
89.9
P-Site Identity:
100
100
73.3
100
N.A.
100
100
N.A.
100
73.3
0
0
N.A.
0
66.6
13.3
66.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
86.6
13.3
13.3
N.A.
20
86.6
33.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
7
0
14
0
7
0
0
0
% D
% Glu:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
14
20
0
7
7
0
0
0
0
0
60
67
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
60
67
0
0
14
0
0
0
7
47
0
0
0
0
0
% H
% Ile:
0
0
7
0
27
0
34
7
0
0
14
60
0
0
0
% I
% Lys:
0
0
0
0
0
0
14
7
0
0
54
0
0
0
0
% K
% Leu:
7
7
7
67
40
7
0
0
0
0
0
14
20
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
7
0
0
0
0
0
0
20
20
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
7
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
14
67
0
0
0
0
0
0
% R
% Ser:
0
14
0
0
0
67
0
0
14
0
7
0
0
0
0
% S
% Thr:
14
7
0
7
0
0
0
0
7
7
0
0
0
0
0
% T
% Val:
0
0
0
0
14
14
40
0
0
7
0
0
7
0
80
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% W
% Tyr:
7
0
67
0
7
0
0
67
0
0
0
0
14
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _