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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2S1
All Species:
37.27
Human Site:
S127
Identified Species:
82
UniProt:
P53680
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53680
NP_004060.2
142
17018
S127
A
G
E
I
R
E
T
S
Q
T
K
V
L
K
Q
Chimpanzee
Pan troglodytes
XP_001168470
158
18910
S143
A
G
E
I
R
E
T
S
Q
T
K
V
L
K
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB50
160
18911
S126
G
G
E
V
Q
E
T
S
K
K
N
V
L
K
A
Rat
Rattus norvegicus
P62744
142
16999
S127
A
G
E
I
R
E
T
S
Q
T
K
V
L
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998320
142
16986
S127
A
G
E
I
R
E
T
S
Q
T
K
V
L
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650961
142
16945
S127
A
G
E
I
R
E
T
S
Q
T
K
V
L
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_508767
142
17064
S127
A
G
E
I
R
E
T
S
Q
T
K
V
L
K
Q
Sea Urchin
Strong. purpuratus
XP_786054
142
16829
S127
A
G
E
I
R
E
T
S
Q
T
K
V
L
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50016
132
15996
D117
V
Y
R
Y
L
I
L
D
E
F
I
L
A
G
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00381
147
17355
S132
G
G
E
I
Q
E
I
S
K
D
M
L
L
E
R
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
S128
A
G
E
I
E
E
T
S
K
Q
V
V
L
T
R
Conservation
Percent
Protein Identity:
100
89.8
N.A.
N.A.
N.A.
43.7
100
N.A.
N.A.
N.A.
N.A.
99.3
N.A.
95.7
N.A.
95
92.2
Protein Similarity:
100
89.8
N.A.
N.A.
N.A.
62.5
100
N.A.
N.A.
N.A.
N.A.
99.3
N.A.
97.1
N.A.
96.4
96.4
P-Site Identity:
100
100
N.A.
N.A.
N.A.
53.3
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
100
N.A.
100
100
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
73.3
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
100
N.A.
100
100
Percent
Protein Identity:
N.A.
61.9
N.A.
N.A.
48.9
67.8
Protein Similarity:
N.A.
74.6
N.A.
N.A.
71.4
79.7
P-Site Identity:
N.A.
0
N.A.
N.A.
40
60
P-Site Similarity:
N.A.
20
N.A.
N.A.
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
73
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% D
% Glu:
0
0
91
0
10
91
0
0
10
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
19
91
0
0
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
82
0
10
10
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
28
10
64
0
0
73
0
% K
% Leu:
0
0
0
0
10
0
10
0
0
0
0
19
91
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
19
0
0
0
64
10
0
0
0
0
64
% Q
% Arg:
0
0
10
0
64
0
0
0
0
0
0
0
0
0
19
% R
% Ser:
0
0
0
0
0
0
0
91
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
82
0
0
64
0
0
0
10
0
% T
% Val:
10
0
0
10
0
0
0
0
0
0
10
82
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _