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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2S1
All Species:
33.03
Human Site:
Y20
Identified Species:
72.67
UniProt:
P53680
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53680
NP_004060.2
142
17018
Y20
K
T
R
L
A
K
W
Y
M
Q
F
D
D
D
E
Chimpanzee
Pan troglodytes
XP_001168470
158
18910
Y36
K
T
R
L
A
K
W
Y
M
Q
F
D
D
D
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB50
160
18911
Y19
K
L
R
L
Q
K
W
Y
V
P
L
S
D
K
E
Rat
Rattus norvegicus
P62744
142
16999
Y20
K
T
R
L
A
K
W
Y
M
Q
F
D
D
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998320
142
16986
Y20
K
T
R
L
A
K
W
Y
M
Q
F
D
D
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650961
142
16945
Y20
K
T
R
L
A
K
W
Y
M
N
F
D
D
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_508767
142
17064
Y20
K
T
R
L
A
K
W
Y
M
H
F
D
D
D
E
Sea Urchin
Strong. purpuratus
XP_786054
142
16829
Y20
K
T
R
L
A
K
W
Y
M
A
F
D
D
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50016
132
15996
K13
L
L
Q
N
R
Q
G
K
T
R
L
A
K
Y
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00381
147
17355
F21
V
V
R
L
V
R
W
F
D
V
H
S
S
D
P
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
Y20
K
T
R
L
A
K
W
Y
V
P
Y
S
D
E
E
Conservation
Percent
Protein Identity:
100
89.8
N.A.
N.A.
N.A.
43.7
100
N.A.
N.A.
N.A.
N.A.
99.3
N.A.
95.7
N.A.
95
92.2
Protein Similarity:
100
89.8
N.A.
N.A.
N.A.
62.5
100
N.A.
N.A.
N.A.
N.A.
99.3
N.A.
97.1
N.A.
96.4
96.4
P-Site Identity:
100
100
N.A.
N.A.
N.A.
53.3
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
93.3
N.A.
93.3
86.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
60
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
93.3
N.A.
93.3
93.3
Percent
Protein Identity:
N.A.
61.9
N.A.
N.A.
48.9
67.8
Protein Similarity:
N.A.
74.6
N.A.
N.A.
71.4
79.7
P-Site Identity:
N.A.
0
N.A.
N.A.
26.6
66.6
P-Site Similarity:
N.A.
20
N.A.
N.A.
40
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
73
0
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
64
82
64
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
82
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
64
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
82
0
0
0
0
82
0
10
0
0
0
0
10
10
0
% K
% Leu:
10
19
0
91
0
0
0
0
0
0
19
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
64
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
10
% P
% Gln:
0
0
10
0
10
10
0
0
0
37
0
0
0
0
0
% Q
% Arg:
0
0
91
0
10
10
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
28
10
0
0
% S
% Thr:
0
73
0
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
10
10
0
0
10
0
0
0
19
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
91
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
10
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _