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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2S1
All Species:
34.24
Human Site:
Y80
Identified Species:
75.33
UniProt:
P53680
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53680
NP_004060.2
142
17018
Y80
V
N
D
N
N
L
A
Y
L
E
A
I
H
N
F
Chimpanzee
Pan troglodytes
XP_001168470
158
18910
Y96
V
N
D
N
N
L
A
Y
L
E
A
I
H
N
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB50
160
18911
T79
D
Q
D
N
E
L
I
T
L
E
I
I
H
R
Y
Rat
Rattus norvegicus
P62744
142
16999
Y80
V
N
D
N
N
L
A
Y
L
E
A
I
H
N
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998320
142
16986
Y80
V
T
D
N
N
L
A
Y
L
E
A
I
H
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650961
142
16945
Y80
V
N
D
N
N
L
C
Y
L
E
A
I
H
N
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_508767
142
17064
Y80
I
T
D
N
N
L
Y
Y
L
E
A
I
H
N
F
Sea Urchin
Strong. purpuratus
XP_786054
142
16829
Y80
V
G
D
N
N
L
A
Y
L
E
A
I
H
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50016
132
15996
C70
A
G
L
F
F
S
I
C
V
D
I
T
D
N
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00381
147
17355
Y85
L
L
D
D
E
P
I
Y
L
C
H
I
H
L
F
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
Y81
T
N
D
N
E
L
A
Y
L
E
A
I
H
F
F
Conservation
Percent
Protein Identity:
100
89.8
N.A.
N.A.
N.A.
43.7
100
N.A.
N.A.
N.A.
N.A.
99.3
N.A.
95.7
N.A.
95
92.2
Protein Similarity:
100
89.8
N.A.
N.A.
N.A.
62.5
100
N.A.
N.A.
N.A.
N.A.
99.3
N.A.
97.1
N.A.
96.4
96.4
P-Site Identity:
100
100
N.A.
N.A.
N.A.
46.6
100
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
93.3
N.A.
80
93.3
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
53.3
100
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
93.3
N.A.
86.6
93.3
Percent
Protein Identity:
N.A.
61.9
N.A.
N.A.
48.9
67.8
Protein Similarity:
N.A.
74.6
N.A.
N.A.
71.4
79.7
P-Site Identity:
N.A.
6.6
N.A.
N.A.
40
80
P-Site Similarity:
N.A.
20
N.A.
N.A.
53.3
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
55
0
0
0
73
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
10
0
10
0
0
0
0
0
% C
% Asp:
10
0
91
10
0
0
0
0
0
10
0
0
10
0
0
% D
% Glu:
0
0
0
0
28
0
0
0
0
82
0
0
0
0
10
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
0
0
0
10
82
% F
% Gly:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
91
0
0
% H
% Ile:
10
0
0
0
0
0
28
0
0
0
19
91
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
10
0
0
82
0
0
91
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
46
0
82
64
0
0
0
0
0
0
0
0
73
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
19
0
0
0
0
0
10
0
0
0
10
0
0
0
% T
% Val:
55
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
82
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _