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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCCS
All Species:
39.39
Human Site:
S114
Identified Species:
57.78
UniProt:
P53701
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53701
NP_001116080.1
268
30602
S114
S
S
I
P
R
A
D
S
E
K
K
W
V
Y
P
Chimpanzee
Pan troglodytes
XP_001142842
269
30427
S114
S
S
I
P
R
A
D
S
E
K
K
W
V
Y
P
Rhesus Macaque
Macaca mulatta
XP_001094078
268
30718
S114
S
S
I
P
R
A
D
S
E
K
K
W
V
Y
P
Dog
Lupus familis
XP_537950
272
31050
S118
S
S
I
P
R
A
D
S
E
K
K
W
V
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
P53702
272
30989
S118
S
S
I
P
R
A
D
S
E
K
K
W
V
Y
P
Rat
Rattus norvegicus
XP_228867
274
31111
S120
S
S
I
P
R
A
D
S
E
K
K
W
V
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506165
272
30773
S118
S
S
I
P
R
A
D
S
E
K
K
W
V
Y
P
Chicken
Gallus gallus
Q5F339
273
31420
S119
S
S
I
P
R
A
H
S
D
K
K
W
V
Y
P
Frog
Xenopus laevis
NP_001087149
267
30990
T113
S
T
I
P
R
S
N
T
E
K
N
W
I
Y
P
Zebra Danio
Brachydanio rerio
NP_958859
269
30882
T115
S
K
I
P
R
S
G
T
E
Q
N
W
V
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651003
281
32005
A124
S
Q
Q
M
F
W
N
A
M
L
R
K
G
W
R
Honey Bee
Apis mellifera
XP_392497
276
32212
A121
S
Q
Q
M
F
W
N
A
M
L
R
K
G
W
R
Nematode Worm
Caenorhab. elegans
P53703
280
31245
F115
T
Y
P
S
P
Q
M
F
W
N
A
M
L
K
K
Sea Urchin
Strong. purpuratus
XP_788812
293
32619
K137
S
G
I
P
R
A
G
K
D
E
N
W
V
Y
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06182
269
30062
V116
K
I
G
G
S
G
E
V
A
E
D
A
V
E
S
Red Bread Mold
Neurospora crassa
P14187
346
38128
G144
S
S
I
P
K
G
T
G
D
G
N
W
E
Y
P
Conservation
Percent
Protein Identity:
100
89.2
98.1
91.1
N.A.
82.7
86.1
N.A.
77.9
75.8
69
68.7
N.A.
52.6
53.9
48.5
56.6
Protein Similarity:
100
92.5
98.8
93.7
N.A.
89.3
90.5
N.A.
88.5
86
83.5
81
N.A.
68.3
66.3
62.1
68.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
60
60
N.A.
6.6
6.6
0
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
80
N.A.
33.3
33.3
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
32
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
57
0
13
7
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
44
0
19
0
7
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
0
57
13
0
0
7
7
0
% E
% Phe:
0
0
0
0
13
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
7
0
13
13
7
0
7
0
0
13
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
75
0
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
7
7
0
0
7
0
0
7
0
57
50
13
0
7
7
% K
% Leu:
0
0
0
0
0
0
0
0
0
13
0
0
7
0
0
% L
% Met:
0
0
0
13
0
0
7
0
13
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
19
0
0
7
25
0
0
0
0
% N
% Pro:
0
0
7
75
7
0
0
0
0
0
0
0
0
0
75
% P
% Gln:
0
13
13
0
0
7
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
69
0
0
0
0
0
13
0
0
0
13
% R
% Ser:
88
57
0
7
7
13
0
50
0
0
0
0
0
0
7
% S
% Thr:
7
7
0
0
0
0
7
13
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
0
0
0
0
69
0
0
% V
% Trp:
0
0
0
0
0
13
0
0
7
0
0
75
0
13
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
75
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _