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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCCS
All Species:
25.45
Human Site:
S23
Identified Species:
37.33
UniProt:
P53701
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53701
NP_001116080.1
268
30602
S23
N
A
S
A
S
P
P
S
G
C
P
M
H
E
G
Chimpanzee
Pan troglodytes
XP_001142842
269
30427
S23
N
A
S
A
S
P
P
S
G
C
P
M
H
E
G
Rhesus Macaque
Macaca mulatta
XP_001094078
268
30718
S23
N
T
S
A
S
P
P
S
G
C
P
M
H
E
G
Dog
Lupus familis
XP_537950
272
31050
S27
R
Q
T
A
S
P
P
S
G
C
P
M
H
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P53702
272
30989
S27
G
Q
P
A
S
P
P
S
G
C
P
M
H
K
G
Rat
Rattus norvegicus
XP_228867
274
31111
S29
P
A
S
A
S
P
P
S
G
C
P
M
H
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506165
272
30773
A23
D
G
S
A
P
R
P
A
S
P
P
S
G
C
P
Chicken
Gallus gallus
Q5F339
273
31420
S29
H
Q
V
A
S
P
P
S
E
C
P
M
H
Q
E
Frog
Xenopus laevis
NP_001087149
267
30990
T23
P
Q
S
S
T
D
S
T
K
T
H
P
A
E
S
Zebra Danio
Brachydanio rerio
NP_958859
269
30882
F23
S
V
I
S
A
P
H
F
A
G
A
S
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651003
281
32005
P33
S
G
S
G
A
P
P
P
E
C
P
M
H
Q
K
Honey Bee
Apis mellifera
XP_392497
276
32212
Q27
Q
Q
Q
I
S
K
T
Q
H
H
E
I
Y
K
S
Nematode Worm
Caenorhab. elegans
P53703
280
31245
A23
D
A
E
R
I
R
K
A
Q
H
S
M
A
A
A
Sea Urchin
Strong. purpuratus
XP_788812
293
32619
A32
A
G
A
P
S
P
P
A
E
C
P
M
H
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06182
269
30062
G25
A
A
V
S
S
M
S
G
C
P
V
M
H
E
S
Red Bread Mold
Neurospora crassa
P14187
346
38128
P50
D
A
L
S
A
H
K
P
V
T
P
A
P
E
P
Conservation
Percent
Protein Identity:
100
89.2
98.1
91.1
N.A.
82.7
86.1
N.A.
77.9
75.8
69
68.7
N.A.
52.6
53.9
48.5
56.6
Protein Similarity:
100
92.5
98.8
93.7
N.A.
89.3
90.5
N.A.
88.5
86
83.5
81
N.A.
68.3
66.3
62.1
68.9
P-Site Identity:
100
100
93.3
80
N.A.
73.3
93.3
N.A.
26.6
60
13.3
6.6
N.A.
46.6
6.6
13.3
53.3
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
93.3
N.A.
40
73.3
33.3
26.6
N.A.
66.6
26.6
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
32
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
38
7
50
19
0
0
19
7
0
7
7
13
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
7
57
0
0
0
7
0
% C
% Asp:
19
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
0
0
0
0
0
19
0
7
0
0
50
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
7
19
0
7
0
0
0
7
38
7
0
0
7
0
44
% G
% His:
7
0
0
0
0
7
7
0
7
13
7
0
63
0
0
% H
% Ile:
0
0
7
7
7
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
0
0
0
0
7
13
0
7
0
0
0
0
13
7
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
69
0
0
0
% M
% Asn:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
0
7
7
7
63
63
13
0
13
69
7
13
7
19
% P
% Gln:
7
32
7
0
0
0
0
7
7
0
0
0
0
19
0
% Q
% Arg:
7
0
0
7
0
13
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
44
25
63
0
13
44
7
0
7
13
0
0
19
% S
% Thr:
0
7
7
0
7
0
7
7
0
13
0
0
0
0
0
% T
% Val:
0
7
13
0
0
0
0
0
7
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _