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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCCS
All Species:
13.33
Human Site:
T50
Identified Species:
19.56
UniProt:
P53701
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53701
NP_001116080.1
268
30602
T50
G
P
T
C
E
K
K
T
Y
S
V
P
A
H
Q
Chimpanzee
Pan troglodytes
XP_001142842
269
30427
T50
G
P
T
C
E
K
K
T
Y
S
V
P
A
H
Q
Rhesus Macaque
Macaca mulatta
XP_001094078
268
30718
T50
G
P
T
C
E
K
K
T
Y
S
M
P
A
H
Q
Dog
Lupus familis
XP_537950
272
31050
M54
D
P
T
C
E
N
K
M
S
S
V
P
A
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
P53702
272
30989
A54
D
L
T
S
E
S
K
A
H
T
V
P
A
H
Q
Rat
Rattus norvegicus
XP_228867
274
31111
A56
D
L
T
S
E
S
K
A
H
S
V
P
A
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506165
272
30773
A54
A
K
P
T
G
S
Q
A
N
S
V
P
A
H
Q
Chicken
Gallus gallus
Q5F339
273
31420
T55
S
D
R
R
A
E
N
T
D
D
V
P
A
H
Q
Frog
Xenopus laevis
NP_001087149
267
30990
N49
M
H
K
E
S
K
Q
N
T
E
N
C
S
G
P
Zebra Danio
Brachydanio rerio
NP_958859
269
30882
Q51
P
P
E
C
P
M
H
Q
A
Q
T
P
P
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651003
281
32005
S60
H
P
K
M
Q
A
A
S
E
C
P
V
Q
H
D
Honey Bee
Apis mellifera
XP_392497
276
32212
S57
E
K
E
S
P
I
L
S
S
E
C
P
I
N
D
Nematode Worm
Caenorhab. elegans
P53703
280
31245
C51
A
A
A
S
G
E
N
C
G
A
G
G
A
C
P
Sea Urchin
Strong. purpuratus
XP_788812
293
32619
D73
A
S
S
A
P
A
R
D
T
S
T
A
A
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06182
269
30062
I52
M
Q
G
D
N
D
R
I
N
P
L
N
N
M
P
Red Bread Mold
Neurospora crassa
P14187
346
38128
A80
A
K
D
T
L
A
A
A
A
A
A
V
A
P
K
Conservation
Percent
Protein Identity:
100
89.2
98.1
91.1
N.A.
82.7
86.1
N.A.
77.9
75.8
69
68.7
N.A.
52.6
53.9
48.5
56.6
Protein Similarity:
100
92.5
98.8
93.7
N.A.
89.3
90.5
N.A.
88.5
86
83.5
81
N.A.
68.3
66.3
62.1
68.9
P-Site Identity:
100
100
93.3
73.3
N.A.
53.3
60
N.A.
40
40
6.6
20
N.A.
13.3
6.6
6.6
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
66.6
66.6
N.A.
46.6
46.6
20
20
N.A.
26.6
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
32
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
7
7
7
7
19
13
25
13
13
7
7
69
7
7
% A
% Cys:
0
0
0
32
0
0
0
7
0
7
7
7
0
7
0
% C
% Asp:
19
7
7
7
0
7
0
7
7
7
0
0
0
0
13
% D
% Glu:
7
0
13
7
38
13
0
0
7
13
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
7
0
13
0
0
0
7
0
7
7
0
7
0
% G
% His:
7
7
0
0
0
0
7
0
13
0
0
0
0
57
0
% H
% Ile:
0
0
0
0
0
7
0
7
0
0
0
0
7
0
7
% I
% Lys:
0
19
13
0
0
25
38
0
0
0
0
0
0
0
7
% K
% Leu:
0
13
0
0
7
0
7
0
0
0
7
0
0
0
0
% L
% Met:
13
0
0
7
0
7
0
7
0
0
7
0
0
7
0
% M
% Asn:
0
0
0
0
7
7
13
7
13
0
7
7
7
7
0
% N
% Pro:
7
38
7
0
19
0
0
0
0
7
7
63
7
7
19
% P
% Gln:
0
7
0
0
7
0
13
7
0
7
0
0
7
0
50
% Q
% Arg:
0
0
7
7
0
0
13
0
0
0
0
0
0
0
0
% R
% Ser:
7
7
7
25
7
19
0
13
13
44
0
0
7
0
0
% S
% Thr:
0
0
38
13
0
0
0
25
13
7
13
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
44
13
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _