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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCCS
All Species:
30.3
Human Site:
Y148
Identified Species:
44.44
UniProt:
P53701
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53701
NP_001116080.1
268
30602
Y148
D
I
S
Q
K
D
M
Y
N
I
I
R
I
H
N
Chimpanzee
Pan troglodytes
XP_001142842
269
30427
F148
K
P
P
Q
R
Q
D
F
S
L
L
R
V
V
V
Rhesus Macaque
Macaca mulatta
XP_001094078
268
30718
Y148
D
I
S
Q
K
D
M
Y
N
I
I
R
I
H
N
Dog
Lupus familis
XP_537950
272
31050
Y152
D
I
S
Q
K
D
M
Y
N
I
I
R
I
H
N
Cat
Felis silvestris
Mouse
Mus musculus
P53702
272
30989
Y152
D
I
S
Q
K
D
M
Y
N
I
I
R
I
H
N
Rat
Rattus norvegicus
XP_228867
274
31111
Y154
D
I
S
Q
K
D
M
Y
N
I
I
R
I
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506165
272
30773
Y152
E
I
N
Q
K
D
M
Y
N
I
I
K
I
H
N
Chicken
Gallus gallus
Q5F339
273
31420
T153
D
I
T
S
E
D
M
T
N
I
I
K
I
H
N
Frog
Xenopus laevis
NP_001087149
267
30990
A147
D
L
K
P
D
D
M
A
N
I
I
K
I
H
N
Zebra Danio
Brachydanio rerio
NP_958859
269
30882
S149
T
L
A
P
E
D
M
S
N
I
I
Q
I
H
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651003
281
32005
W157
N
A
N
N
E
Q
A
W
Q
E
V
L
K
W
E
Honey Bee
Apis mellifera
XP_392497
276
32212
N149
I
I
K
I
H
N
A
N
N
E
L
A
W
Q
E
Nematode Worm
Caenorhab. elegans
P53703
280
31245
L155
E
E
A
W
R
E
V
L
K
W
E
N
L
L
H
Sea Urchin
Strong. purpuratus
XP_788812
293
32619
H171
D
I
Q
Q
E
D
M
H
N
I
I
H
I
H
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06182
269
30062
P145
E
V
L
E
W
E
K
P
H
T
D
E
S
H
V
Red Bread Mold
Neurospora crassa
P14187
346
38128
E174
D
T
D
I
T
A
V
E
S
M
V
A
V
H
N
Conservation
Percent
Protein Identity:
100
89.2
98.1
91.1
N.A.
82.7
86.1
N.A.
77.9
75.8
69
68.7
N.A.
52.6
53.9
48.5
56.6
Protein Similarity:
100
92.5
98.8
93.7
N.A.
89.3
90.5
N.A.
88.5
86
83.5
81
N.A.
68.3
66.3
62.1
68.9
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
80
66.6
60
53.3
N.A.
0
13.3
0
73.3
P-Site Similarity:
100
53.3
100
100
N.A.
100
100
N.A.
100
86.6
73.3
80
N.A.
33.3
26.6
46.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
32
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
13
0
0
7
13
7
0
0
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
57
0
7
0
7
63
7
0
0
0
7
0
0
0
0
% D
% Glu:
19
7
0
7
25
13
0
7
0
13
7
7
0
0
13
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
7
7
0
0
7
0
75
7
% H
% Ile:
7
57
0
13
0
0
0
0
0
63
63
0
63
0
0
% I
% Lys:
7
0
13
0
38
0
7
0
7
0
0
19
7
0
0
% K
% Leu:
0
13
7
0
0
0
0
7
0
7
13
7
7
7
0
% L
% Met:
0
0
0
0
0
0
63
0
0
7
0
0
0
0
0
% M
% Asn:
7
0
13
7
0
7
0
7
69
0
0
7
0
0
69
% N
% Pro:
0
7
7
13
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
50
0
13
0
0
7
0
0
7
0
7
0
% Q
% Arg:
0
0
0
0
13
0
0
0
0
0
0
38
0
0
0
% R
% Ser:
0
0
32
7
0
0
0
7
13
0
0
0
7
0
0
% S
% Thr:
7
7
7
0
7
0
0
7
0
7
0
0
0
0
0
% T
% Val:
0
7
0
0
0
0
13
0
0
0
13
0
13
7
13
% V
% Trp:
0
0
0
7
7
0
0
7
0
7
0
0
7
7
0
% W
% Tyr:
0
0
0
0
0
0
0
38
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _