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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCCS
All Species:
15.76
Human Site:
Y51
Identified Species:
23.11
UniProt:
P53701
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53701
NP_001116080.1
268
30602
Y51
P
T
C
E
K
K
T
Y
S
V
P
A
H
Q
E
Chimpanzee
Pan troglodytes
XP_001142842
269
30427
Y51
P
T
C
E
K
K
T
Y
S
V
P
A
H
Q
E
Rhesus Macaque
Macaca mulatta
XP_001094078
268
30718
Y51
P
T
C
E
K
K
T
Y
S
M
P
A
H
Q
E
Dog
Lupus familis
XP_537950
272
31050
S55
P
T
C
E
N
K
M
S
S
V
P
A
H
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
P53702
272
30989
H55
L
T
S
E
S
K
A
H
T
V
P
A
H
Q
D
Rat
Rattus norvegicus
XP_228867
274
31111
H57
L
T
S
E
S
K
A
H
S
V
P
A
H
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506165
272
30773
N55
K
P
T
G
S
Q
A
N
S
V
P
A
H
Q
D
Chicken
Gallus gallus
Q5F339
273
31420
D56
D
R
R
A
E
N
T
D
D
V
P
A
H
Q
E
Frog
Xenopus laevis
NP_001087149
267
30990
T50
H
K
E
S
K
Q
N
T
E
N
C
S
G
P
V
Zebra Danio
Brachydanio rerio
NP_958859
269
30882
A52
P
E
C
P
M
H
Q
A
Q
T
P
P
A
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651003
281
32005
E61
P
K
M
Q
A
A
S
E
C
P
V
Q
H
D
N
Honey Bee
Apis mellifera
XP_392497
276
32212
S58
K
E
S
P
I
L
S
S
E
C
P
I
N
D
M
Nematode Worm
Caenorhab. elegans
P53703
280
31245
G52
A
A
S
G
E
N
C
G
A
G
G
A
C
P
V
Sea Urchin
Strong. purpuratus
XP_788812
293
32619
T74
S
S
A
P
A
R
D
T
S
T
A
A
V
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06182
269
30062
N53
Q
G
D
N
D
R
I
N
P
L
N
N
M
P
E
Red Bread Mold
Neurospora crassa
P14187
346
38128
A81
K
D
T
L
A
A
A
A
A
A
V
A
P
K
Q
Conservation
Percent
Protein Identity:
100
89.2
98.1
91.1
N.A.
82.7
86.1
N.A.
77.9
75.8
69
68.7
N.A.
52.6
53.9
48.5
56.6
Protein Similarity:
100
92.5
98.8
93.7
N.A.
89.3
90.5
N.A.
88.5
86
83.5
81
N.A.
68.3
66.3
62.1
68.9
P-Site Identity:
100
100
93.3
73.3
N.A.
53.3
60
N.A.
40
46.6
6.6
20
N.A.
13.3
6.6
6.6
13.3
P-Site Similarity:
100
100
100
80
N.A.
73.3
73.3
N.A.
53.3
53.3
20
20
N.A.
26.6
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
32
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
19
13
25
13
13
7
7
69
7
7
0
% A
% Cys:
0
0
32
0
0
0
7
0
7
7
7
0
7
0
0
% C
% Asp:
7
7
7
0
7
0
7
7
7
0
0
0
0
13
25
% D
% Glu:
0
13
7
38
13
0
0
7
13
0
0
0
0
0
32
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
13
0
0
0
7
0
7
7
0
7
0
0
% G
% His:
7
0
0
0
0
7
0
13
0
0
0
0
57
0
0
% H
% Ile:
0
0
0
0
7
0
7
0
0
0
0
7
0
7
0
% I
% Lys:
19
13
0
0
25
38
0
0
0
0
0
0
0
7
0
% K
% Leu:
13
0
0
7
0
7
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
7
0
7
0
7
0
0
7
0
0
7
0
7
% M
% Asn:
0
0
0
7
7
13
7
13
0
7
7
7
7
0
7
% N
% Pro:
38
7
0
19
0
0
0
0
7
7
63
7
7
19
13
% P
% Gln:
7
0
0
7
0
13
7
0
7
0
0
7
0
50
7
% Q
% Arg:
0
7
7
0
0
13
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
7
25
7
19
0
13
13
44
0
0
7
0
0
0
% S
% Thr:
0
38
13
0
0
0
25
13
7
13
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
44
13
0
7
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _