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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HCCS
All Species:
30
Human Site:
Y63
Identified Species:
44
UniProt:
P53701
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53701
NP_001116080.1
268
30602
Y63
H
Q
E
R
A
Y
E
Y
V
E
C
P
I
R
G
Chimpanzee
Pan troglodytes
XP_001142842
269
30427
Y63
H
Q
E
R
A
Y
E
Y
V
E
C
P
I
R
G
Rhesus Macaque
Macaca mulatta
XP_001094078
268
30718
Y63
H
Q
E
R
A
Y
E
Y
V
E
C
P
I
R
G
Dog
Lupus familis
XP_537950
272
31050
Y67
H
Q
D
R
A
Y
E
Y
V
E
C
P
V
T
G
Cat
Felis silvestris
Mouse
Mus musculus
P53702
272
30989
Y67
H
Q
D
R
A
Y
D
Y
V
E
C
P
V
T
G
Rat
Rattus norvegicus
XP_228867
274
31111
Y69
H
Q
D
R
A
Y
E
Y
V
E
C
P
V
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506165
272
30773
Y67
H
Q
D
R
A
Y
E
Y
V
E
C
P
V
K
S
Chicken
Gallus gallus
Q5F339
273
31420
Y68
H
Q
E
R
A
Y
E
Y
V
A
C
P
V
K
S
Frog
Xenopus laevis
NP_001087149
267
30990
A62
G
P
V
H
Q
E
E
A
Y
A
Y
V
Q
C
P
Zebra Danio
Brachydanio rerio
NP_958859
269
30882
R64
A
A
P
V
H
Q
E
R
A
Y
E
F
V
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651003
281
32005
P73
H
D
N
S
D
V
N
P
L
N
M
M
P
P
A
Honey Bee
Apis mellifera
XP_392497
276
32212
I70
N
D
M
T
S
E
D
I
N
P
L
N
M
M
P
Nematode Worm
Caenorhab. elegans
P53703
280
31245
A64
C
P
V
G
A
D
K
A
S
I
N
P
L
N
N
Sea Urchin
Strong. purpuratus
XP_788812
293
32619
M86
V
I
P
S
E
C
P
M
S
G
G
T
N
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06182
269
30062
K65
M
P
E
L
A
A
S
K
Q
P
G
Q
K
M
D
Red Bread Mold
Neurospora crassa
P14187
346
38128
N93
P
K
Q
P
Q
P
E
N
H
Q
P
A
A
A
S
Conservation
Percent
Protein Identity:
100
89.2
98.1
91.1
N.A.
82.7
86.1
N.A.
77.9
75.8
69
68.7
N.A.
52.6
53.9
48.5
56.6
Protein Similarity:
100
92.5
98.8
93.7
N.A.
89.3
90.5
N.A.
88.5
86
83.5
81
N.A.
68.3
66.3
62.1
68.9
P-Site Identity:
100
100
100
80
N.A.
73.3
80
N.A.
73.3
73.3
6.6
6.6
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
6.6
13.3
N.A.
13.3
26.6
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
32
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.4
43.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
63
7
0
13
7
13
0
7
7
13
7
% A
% Cys:
7
0
0
0
0
7
0
0
0
0
50
0
0
7
7
% C
% Asp:
0
13
25
0
7
7
13
0
0
0
0
0
0
0
7
% D
% Glu:
0
0
32
0
7
13
63
0
0
44
7
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
7
0
0
7
0
0
0
0
0
7
13
0
0
0
38
% G
% His:
57
0
0
7
7
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
7
0
7
0
0
19
0
0
% I
% Lys:
0
7
0
0
0
0
7
7
0
0
0
0
7
13
0
% K
% Leu:
0
0
0
7
0
0
0
0
7
0
7
0
7
0
7
% L
% Met:
7
0
7
0
0
0
0
7
0
0
7
7
7
13
0
% M
% Asn:
7
0
7
0
0
0
7
7
7
7
7
7
7
7
7
% N
% Pro:
7
19
13
7
0
7
7
7
0
13
7
57
7
7
13
% P
% Gln:
0
50
7
0
13
7
0
0
7
7
0
7
7
0
0
% Q
% Arg:
0
0
0
50
0
0
0
7
0
0
0
0
0
19
0
% R
% Ser:
0
0
0
13
7
0
7
0
13
0
0
0
0
0
19
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
0
7
0
19
0
% T
% Val:
7
0
13
7
0
7
0
0
50
0
0
7
38
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
50
0
50
7
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _