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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITGA8 All Species: 8.48
Human Site: S12 Identified Species: 16.97
UniProt: P53708 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53708 NP_003629.1 1063 117446 S12 A S R G P R G S Q A P L I A P
Chimpanzee Pan troglodytes XP_507671 1063 117421 S12 A S R G P R G S Q A P L I A P
Rhesus Macaque Macaca mulatta XP_001089317 1063 117513 S12 A S R G P W G S R T P L I A P
Dog Lupus familis XP_544247 1043 115480 R12 H L E P E T C R L H R Q R Q S
Cat Felis silvestris
Mouse Mus musculus A2ARA8 1062 117537 N12 T H C G P P G N R A P P F A R
Rat Rattus norvegicus Q63258 1135 124176 G14 C D F L G L P G I C Y L L S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508582 998 109248 A12 G L L A P A P A V S S P A H A
Chicken Gallus gallus P26009 1044 116123 L12 Q P P R P L L L L S A L L C A
Frog Xenopus laevis Q06274 1050 115944 L12 R G S R V P G L V A T F L F P
Zebra Danio Brachydanio rerio NP_001028893 1045 114991 A12 F V R C W L W A L V A L F T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P12080 1396 154303 A12 S I H R R R M A L H C P I T S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34446 1226 135921 L12 S F P R R I G L L L G L L G L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.4 86.2 N.A. 89 29.5 N.A. 70.3 75.7 45.3 46 N.A. 26 N.A. 29.2 N.A.
Protein Similarity: 100 99.6 98.6 91.6 N.A. 95.3 45 N.A. 81 86.2 63.5 64.5 N.A. 42.1 N.A. 46.9 N.A.
P-Site Identity: 100 100 80 0 N.A. 40 6.6 N.A. 6.6 13.3 20 13.3 N.A. 13.3 N.A. 13.3 N.A.
P-Site Similarity: 100 100 86.6 0 N.A. 53.3 20 N.A. 20 26.6 26.6 20 N.A. 26.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 0 9 0 9 0 25 0 34 17 0 9 34 17 % A
% Cys: 9 0 9 9 0 0 9 0 0 9 9 0 0 9 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 9 9 0 0 0 0 0 0 0 0 9 17 9 9 % F
% Gly: 9 9 0 34 9 0 50 9 0 0 9 0 0 9 0 % G
% His: 9 9 9 0 0 0 0 0 0 17 0 0 0 9 0 % H
% Ile: 0 9 0 0 0 9 0 0 9 0 0 0 34 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 17 9 9 0 25 9 25 42 9 0 59 34 0 9 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 9 17 9 50 17 17 0 0 0 34 25 0 0 34 % P
% Gln: 9 0 0 0 0 0 0 0 17 0 0 9 0 9 0 % Q
% Arg: 9 0 34 34 17 25 0 9 17 0 9 0 9 0 9 % R
% Ser: 17 25 9 0 0 0 0 25 0 17 9 0 0 9 17 % S
% Thr: 9 0 0 0 0 9 0 0 0 9 9 0 0 17 9 % T
% Val: 0 9 0 0 9 0 0 0 17 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 9 9 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _