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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK10 All Species: 14.55
Human Site: T216 Identified Species: 26.67
UniProt: P53779 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53779 NP_002744.1 464 52585 T216 G L A R T A G T S F M M T P Y
Chimpanzee Pan troglodytes Q9N272 365 41989 S123 K I M X M E F S E E K I Q Y L
Rhesus Macaque Macaca mulatta XP_001094539 426 47882 P184 G T S F M M T P Y V V T R Y Y
Dog Lupus familis XP_535641 464 52533 T216 G L A R T A G T S F M M T P Y
Cat Felis silvestris
Mouse Mus musculus Q61831 464 52514 T216 G L A R T A G T S F M M T P Y
Rat Rattus norvegicus P49187 464 52512 T216 G L A R T A G T S F M M T P Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513255 564 63642 Q291 R M S Y L L Y Q M L C G I K H
Chicken Gallus gallus P79996 382 43990 K140 Y Q M L C G I K H L H S A G I
Frog Xenopus laevis Q8QHK8 426 47910 P184 G T S F M M T P Y V V T R Y Y
Zebra Danio Brachydanio rerio Q9DGD9 384 44121 L142 M L C G I K H L H A A G I I H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P92208 372 43008 L129 D H D R M S Y L L Y Q M L C G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q8WQG9 463 52867 I212 D A N L C Q V I Q M D L D H E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32485 435 48840 K193 E I M L T W Q K Y D V E V D I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39 90 99.7 N.A. 98.7 98.7 N.A. 72.3 70.4 79.7 70.2 N.A. 62.7 N.A. 59 N.A.
Protein Similarity: 100 52.5 91.1 99.7 N.A. 98.9 98.9 N.A. 75.5 76.5 84.9 77.1 N.A. 70.9 N.A. 70.9 N.A.
P-Site Identity: 100 0 13.3 100 N.A. 100 100 N.A. 0 0 13.3 6.6 N.A. 13.3 N.A. 0 N.A.
P-Site Similarity: 100 20 26.6 100 N.A. 100 100 N.A. 20 0 26.6 13.3 N.A. 26.6 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 31 0 0 31 0 0 0 8 8 0 8 0 0 % A
% Cys: 0 0 8 0 16 0 0 0 0 0 8 0 0 8 0 % C
% Asp: 16 0 8 0 0 0 0 0 0 8 8 0 8 8 0 % D
% Glu: 8 0 0 0 0 8 0 0 8 8 0 8 0 0 8 % E
% Phe: 0 0 0 16 0 0 8 0 0 31 0 0 0 0 0 % F
% Gly: 47 0 0 8 0 8 31 0 0 0 0 16 0 8 8 % G
% His: 0 8 0 0 0 0 8 0 16 0 8 0 0 8 16 % H
% Ile: 0 16 0 0 8 0 8 8 0 0 0 8 16 8 16 % I
% Lys: 8 0 0 0 0 8 0 16 0 0 8 0 0 8 0 % K
% Leu: 0 39 0 24 8 8 0 16 8 16 0 8 8 0 8 % L
% Met: 8 8 24 0 31 16 0 0 8 8 31 39 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 16 0 0 0 0 0 31 0 % P
% Gln: 0 8 0 0 0 8 8 8 8 0 8 0 8 0 0 % Q
% Arg: 8 0 0 39 0 0 0 0 0 0 0 0 16 0 0 % R
% Ser: 0 0 24 0 0 8 0 8 31 0 0 8 0 0 0 % S
% Thr: 0 16 0 0 39 0 16 31 0 0 0 16 31 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 16 24 0 8 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 0 0 16 0 24 8 0 0 0 24 47 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _