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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK10
All Species:
14.85
Human Site:
Y223
Identified Species:
27.22
UniProt:
P53779
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53779
NP_002744.1
464
52585
Y223
T
S
F
M
M
T
P
Y
V
V
T
R
Y
Y
R
Chimpanzee
Pan troglodytes
Q9N272
365
41989
L130
S
E
E
K
I
Q
Y
L
V
Y
Q
M
L
K
G
Rhesus Macaque
Macaca mulatta
XP_001094539
426
47882
Y191
P
Y
V
V
T
R
Y
Y
R
A
P
E
V
I
L
Dog
Lupus familis
XP_535641
464
52533
Y223
T
S
F
M
M
T
P
Y
V
V
T
R
Y
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61831
464
52514
Y223
T
S
F
M
M
T
P
Y
V
V
T
R
Y
Y
R
Rat
Rattus norvegicus
P49187
464
52512
Y223
T
S
F
M
M
T
P
Y
V
V
T
R
Y
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513255
564
63642
H298
Q
M
L
C
G
I
K
H
L
H
S
A
G
I
I
Chicken
Gallus gallus
P79996
382
43990
I147
K
H
L
H
S
A
G
I
I
H
R
D
L
K
P
Frog
Xenopus laevis
Q8QHK8
426
47910
Y191
P
Y
V
V
T
R
Y
Y
R
A
P
E
V
I
L
Zebra Danio
Brachydanio rerio
Q9DGD9
384
44121
H149
L
H
A
A
G
I
I
H
R
D
L
K
P
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P92208
372
43008
G136
L
L
Y
Q
M
L
C
G
I
K
H
L
H
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8WQG9
463
52867
E219
I
Q
M
D
L
D
H
E
R
L
S
Y
L
L
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32485
435
48840
I200
K
Y
D
V
E
V
D
I
W
S
A
G
C
I
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39
90
99.7
N.A.
98.7
98.7
N.A.
72.3
70.4
79.7
70.2
N.A.
62.7
N.A.
59
N.A.
Protein Similarity:
100
52.5
91.1
99.7
N.A.
98.9
98.9
N.A.
75.5
76.5
84.9
77.1
N.A.
70.9
N.A.
70.9
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
0
0
6.6
0
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
20
13.3
100
N.A.
100
100
N.A.
20
6.6
13.3
13.3
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
0
0
0
16
8
8
0
0
8
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
8
0
8
8
0
0
8
0
8
0
0
0
% D
% Glu:
0
8
8
0
8
0
0
8
0
0
0
16
0
0
0
% E
% Phe:
0
0
31
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
16
0
8
8
0
0
0
8
8
0
8
% G
% His:
0
16
0
8
0
0
8
16
0
16
8
0
8
0
0
% H
% Ile:
8
0
0
0
8
16
8
16
16
0
0
0
0
31
8
% I
% Lys:
16
0
0
8
0
0
8
0
0
8
0
8
0
16
0
% K
% Leu:
16
8
16
0
8
8
0
8
8
8
8
8
24
8
16
% L
% Met:
0
8
8
31
39
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
16
0
0
0
0
0
31
0
0
0
16
0
8
0
8
% P
% Gln:
8
8
0
8
0
8
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
16
0
0
31
0
8
31
0
0
31
% R
% Ser:
8
31
0
0
8
0
0
0
0
8
16
0
0
16
0
% S
% Thr:
31
0
0
0
16
31
0
0
0
0
31
0
0
0
0
% T
% Val:
0
0
16
24
0
8
0
0
39
31
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
24
8
0
0
0
24
47
0
8
0
8
31
31
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _