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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK10
All Species:
14.85
Human Site:
Y395
Identified Species:
27.22
UniProt:
P53779
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53779
NP_002744.1
464
52585
Y395
E
E
W
K
E
L
I
Y
K
E
V
M
N
S
E
Chimpanzee
Pan troglodytes
Q9N272
365
41989
L297
E
L
D
V
D
K
R
L
T
A
A
Q
A
L
T
Rhesus Macaque
Macaca mulatta
XP_001094539
426
47882
K358
E
W
K
E
L
I
Y
K
E
V
M
N
S
E
E
Dog
Lupus familis
XP_535641
464
52533
Y395
E
E
W
K
E
L
I
Y
K
E
V
M
N
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61831
464
52514
Y395
E
E
W
K
E
L
I
Y
K
E
V
M
N
S
E
Rat
Rattus norvegicus
P49187
464
52512
Y395
E
E
W
K
E
L
I
Y
K
E
V
M
N
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513255
564
63642
P491
P
A
E
V
E
A
P
P
P
Q
I
Y
D
K
Q
Chicken
Gallus gallus
P79996
382
43990
E314
D
K
R
I
S
V
D
E
A
L
R
H
P
Y
I
Frog
Xenopus laevis
Q8QHK8
426
47910
K358
E
W
K
E
L
I
Y
K
E
V
L
D
W
E
E
Zebra Danio
Brachydanio rerio
Q9DGD9
384
44121
L316
R
I
S
V
D
E
A
L
Q
H
P
Y
I
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P92208
372
43008
I303
L
L
S
K
M
L
V
I
D
P
E
Q
R
I
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8WQG9
463
52867
M394
A
R
D
L
L
S
R
M
L
V
I
D
P
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32485
435
48840
T367
D
D
Q
V
A
A
A
T
A
A
A
A
Q
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39
90
99.7
N.A.
98.7
98.7
N.A.
72.3
70.4
79.7
70.2
N.A.
62.7
N.A.
59
N.A.
Protein Similarity:
100
52.5
91.1
99.7
N.A.
98.9
98.9
N.A.
75.5
76.5
84.9
77.1
N.A.
70.9
N.A.
70.9
N.A.
P-Site Identity:
100
6.6
13.3
100
N.A.
100
100
N.A.
6.6
0
13.3
0
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
13.3
46.6
100
N.A.
100
100
N.A.
33.3
20
40
20
N.A.
20
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
16
16
0
16
16
16
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
8
16
0
16
0
8
0
8
0
0
16
8
0
0
% D
% Glu:
54
31
8
16
39
8
0
8
16
31
8
0
0
24
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
8
0
8
0
16
31
8
0
0
16
0
8
8
8
% I
% Lys:
0
8
16
39
0
8
0
16
31
0
0
0
0
8
0
% K
% Leu:
8
16
0
8
24
39
0
16
8
8
8
0
0
8
0
% L
% Met:
0
0
0
0
8
0
0
8
0
0
8
31
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
31
8
0
% N
% Pro:
8
0
0
0
0
0
8
8
8
8
8
0
16
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
8
0
16
8
0
16
% Q
% Arg:
8
8
8
0
0
0
16
0
0
0
8
0
8
0
8
% R
% Ser:
0
0
16
0
8
8
0
0
0
0
0
0
8
31
8
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% T
% Val:
0
0
0
31
0
8
8
0
0
24
31
0
0
0
8
% V
% Trp:
0
16
31
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
16
31
0
0
0
16
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _