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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK10
All Species:
14.55
Human Site:
Y8
Identified Species:
26.67
UniProt:
P53779
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53779
NP_002744.1
464
52585
Y8
M
S
L
H
F
L
Y
Y
C
S
E
P
T
L
D
Chimpanzee
Pan troglodytes
Q9N272
365
41989
Rhesus Macaque
Macaca mulatta
XP_001094539
426
47882
Dog
Lupus familis
XP_535641
464
52533
Y8
M
S
L
H
L
L
Y
Y
C
S
E
P
T
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61831
464
52514
Y8
M
S
L
H
F
L
Y
Y
C
S
E
P
T
L
D
Rat
Rattus norvegicus
P49187
464
52512
Y8
M
S
L
H
F
L
Y
Y
C
S
E
P
T
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513255
564
63642
K46
P
A
K
A
E
A
E
K
C
N
E
C
S
S
R
Chicken
Gallus gallus
P79996
382
43990
Frog
Xenopus laevis
Q8QHK8
426
47910
Zebra Danio
Brachydanio rerio
Q9DGD9
384
44121
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P92208
372
43008
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8WQG9
463
52867
T8
M
E
E
R
L
S
T
T
S
S
Y
P
S
H
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32485
435
48840
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39
90
99.7
N.A.
98.7
98.7
N.A.
72.3
70.4
79.7
70.2
N.A.
62.7
N.A.
59
N.A.
Protein Similarity:
100
52.5
91.1
99.7
N.A.
98.9
98.9
N.A.
75.5
76.5
84.9
77.1
N.A.
70.9
N.A.
70.9
N.A.
P-Site Identity:
100
0
0
93.3
N.A.
100
100
N.A.
13.3
0
0
0
N.A.
0
N.A.
20
N.A.
P-Site Similarity:
100
0
0
93.3
N.A.
100
100
N.A.
33.3
0
0
0
N.A.
0
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
39
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% D
% Glu:
0
8
8
0
8
0
8
0
0
0
39
0
0
0
0
% E
% Phe:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
31
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
31
0
16
31
0
0
0
0
0
0
0
31
0
% L
% Met:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
39
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
31
0
0
0
8
0
0
8
39
0
0
16
8
0
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
0
0
31
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
31
31
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _