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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2K
All Species:
9.09
Human Site:
S30
Identified Species:
16.67
UniProt:
P53803
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53803
NP_005025.1
58
7004
S30
H
T
E
N
E
I
K
S
R
D
P
I
R
C
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q63871
58
6956
S30
H
T
E
N
E
I
K
S
R
D
P
I
R
C
R
Rat
Rattus norvegicus
XP_002725788
107
12353
S58
H
T
E
N
E
I
K
S
R
D
P
I
R
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231230
58
6956
A30
H
T
E
N
E
I
K
A
R
D
P
I
R
C
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665538
58
6970
A30
H
T
E
N
E
I
K
A
R
D
P
I
R
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097319
57
6823
R30
H
E
N
E
M
R
P
R
D
P
I
R
C
R
E
Honey Bee
Apis mellifera
XP_001122738
50
6000
D24
I
C
G
E
C
H
H
D
N
E
I
R
P
R
D
Nematode Worm
Caenorhab. elegans
NP_501593
62
7059
P34
H
A
E
N
E
I
K
P
K
D
A
I
R
C
R
Sea Urchin
Strong. purpuratus
XP_782969
64
7280
A36
H
Q
E
N
E
I
R
A
R
D
P
I
R
C
R
Poplar Tree
Populus trichocarpa
XP_002317630
51
5962
D25
E
N
T
L
K
P
G
D
V
I
Q
C
R
E
C
Maize
Zea mays
NP_001151371
52
6030
D26
E
N
T
L
K
P
G
D
V
I
Q
C
R
E
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_198917
51
5878
D25
E
N
T
L
K
S
G
D
V
I
Q
C
R
E
C
Baker's Yeast
Sacchar. cerevisiae
P40422
70
7697
R42
S
S
K
L
S
L
S
R
T
D
A
V
R
C
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
98.2
50.4
N.A.
N.A.
96.5
N.A.
94.8
N.A.
70.6
63.7
61.2
73.4
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
98.2
52.3
N.A.
N.A.
100
N.A.
100
N.A.
74.1
72.4
72.5
78.1
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
93.3
N.A.
N.A.
93.3
N.A.
93.3
N.A.
6.6
0
73.3
80
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
6.6
6.6
80
93.3
Percent
Protein Identity:
55.1
55.1
N.A.
53.4
35.7
N.A.
Protein Similarity:
72.4
74.1
N.A.
72.4
55.7
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
20
N.A.
P-Site Similarity:
13.3
13.3
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
24
0
0
16
0
0
0
0
% A
% Cys:
0
8
0
0
8
0
0
0
0
0
0
24
8
62
24
% C
% Asp:
0
0
0
0
0
0
0
31
8
62
0
0
0
0
8
% D
% Glu:
24
8
54
16
54
0
0
0
0
8
0
0
0
24
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
24
0
0
0
0
0
0
0
0
% G
% His:
62
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
54
0
0
0
24
16
54
0
0
0
% I
% Lys:
0
0
8
0
24
0
47
0
8
0
0
0
0
0
16
% K
% Leu:
0
0
0
31
0
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
24
8
54
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
16
8
8
0
8
47
0
8
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
24
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
16
47
0
0
16
85
16
47
% R
% Ser:
8
8
0
0
8
8
8
24
0
0
0
0
0
0
0
% S
% Thr:
0
39
24
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
24
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _