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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2K
All Species:
26.36
Human Site:
T49
Identified Species:
48.33
UniProt:
P53803
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53803
NP_005025.1
58
7004
T49
R
I
M
Y
K
K
R
T
K
R
L
V
V
F
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q63871
58
6956
T49
R
I
M
Y
K
K
R
T
K
R
L
V
V
F
D
Rat
Rattus norvegicus
XP_002725788
107
12353
T77
R
I
M
Y
K
K
R
T
K
R
L
M
V
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231230
58
6956
T49
R
I
M
Y
K
K
R
T
K
R
L
V
V
F
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665538
58
6970
T49
R
I
M
Y
K
K
R
T
K
R
L
V
V
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097319
57
6823
K49
I
M
Y
K
K
R
T
K
R
L
V
V
F
D
A
Honey Bee
Apis mellifera
XP_001122738
50
6000
M43
R
E
C
G
Y
R
I
M
Y
K
K
R
T
K
R
Nematode Worm
Caenorhab. elegans
NP_501593
62
7059
C53
R
I
L
Y
K
K
R
C
R
K
L
M
V
Y
D
Sea Urchin
Strong. purpuratus
XP_782969
64
7280
T55
R
I
M
Y
K
K
R
T
K
R
M
V
V
F
D
Poplar Tree
Populus trichocarpa
XP_002317630
51
5962
R44
L
Y
K
K
R
T
R
R
I
V
Q
Y
E
A
R
Maize
Zea mays
NP_001151371
52
6030
R45
L
Y
K
K
R
T
R
R
I
V
Q
Y
E
A
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_198917
51
5878
R44
L
Y
K
K
R
T
R
R
V
V
Q
Y
E
A
R
Baker's Yeast
Sacchar. cerevisiae
P40422
70
7697
T61
R
I
L
L
K
A
R
T
K
R
L
V
Q
F
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
98.2
50.4
N.A.
N.A.
96.5
N.A.
94.8
N.A.
70.6
63.7
61.2
73.4
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
98.2
52.3
N.A.
N.A.
100
N.A.
100
N.A.
74.1
72.4
72.5
78.1
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
93.3
N.A.
N.A.
100
N.A.
100
N.A.
13.3
6.6
60
93.3
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
40
20
93.3
100
Percent
Protein Identity:
55.1
55.1
N.A.
53.4
35.7
N.A.
Protein Similarity:
72.4
74.1
N.A.
72.4
55.7
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
66.6
N.A.
P-Site Similarity:
13.3
13.3
N.A.
13.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
24
8
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
54
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
24
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
54
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
62
0
0
0
0
8
0
16
0
0
0
0
0
0
% I
% Lys:
0
0
24
31
70
54
0
8
54
16
8
0
0
8
0
% K
% Leu:
24
0
16
8
0
0
0
0
0
8
54
0
0
0
0
% L
% Met:
0
8
47
0
0
0
0
8
0
0
8
16
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
24
0
8
0
0
% Q
% Arg:
70
0
0
0
24
16
85
24
16
54
0
8
0
0
31
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
24
8
54
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
24
8
54
54
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
24
8
54
8
0
0
0
8
0
0
24
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _