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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC16A1
All Species:
14.03
Human Site:
S498
Identified Species:
34.29
UniProt:
P53985
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53985
NP_003042.3
500
53958
S498
G
G
P
K
E
E
E
S
P
V
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001154930
500
54002
S498
G
G
P
K
E
E
E
S
P
V
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001108968
500
54138
S498
E
G
P
K
E
E
D
S
P
V
_
_
_
_
_
Dog
Lupus familis
XP_533065
498
53729
S496
G
S
P
K
E
E
E
S
P
V
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P53986
493
53249
Rat
Rattus norvegicus
P53987
494
53220
E491
S
G
D
P
A
E
E
E
S
P
V
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507625
505
54478
G502
E
E
I
A
K
E
A
G
N
R
I
_
_
_
_
Chicken
Gallus gallus
Q90632
542
58161
T536
A
G
C
N
A
D
Q
T
V
E
R
D
S
F
_
Frog
Xenopus laevis
Q6GM59
460
50319
A458
G
D
V
S
C
L
N
A
I
S
_
_
_
_
_
Zebra Danio
Brachydanio rerio
Q503M4
477
51835
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97
88.8
N.A.
86.1
84.8
N.A.
80.5
39.4
30.3
32.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
98.5
94.4
N.A.
90.8
91.1
N.A.
89.6
58.2
50
49.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
90
N.A.
0
27.2
N.A.
9
7.1
10
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
90
90
N.A.
0
27.2
N.A.
27.2
28.5
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
20
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
10
10
0
0
0
0
10
0
0
0
% D
% Glu:
20
10
0
0
40
60
40
10
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
40
50
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
10
0
10
0
0
0
0
% I
% Lys:
0
0
0
40
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
40
10
0
0
0
0
40
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% R
% Ser:
10
10
0
10
0
0
0
40
10
10
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
10
40
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
50
70
70
70
80
% _