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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC16A1 All Species: 22.73
Human Site: Y140 Identified Species: 55.56
UniProt: P53985 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53985 NP_003042.3 500 53958 Y140 T M I G K Y F Y K R R P L A N
Chimpanzee Pan troglodytes XP_001154930 500 54002 Y140 T M I G K Y F Y K R R P L A N
Rhesus Macaque Macaca mulatta XP_001108968 500 54138 Y140 T M I G K Y F Y K R R P L A N
Dog Lupus familis XP_533065 498 53729 Y140 T M I G K Y F Y K R R P L A N
Cat Felis silvestris
Mouse Mus musculus P53986 493 53249 Y140 T M I G K Y F Y K K R P L A N
Rat Rattus norvegicus P53987 494 53220 Y140 T M I G K Y F Y K K R P L A N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507625 505 54478 F140 T M I G K Y F F K K R P L A N
Chicken Gallus gallus Q90632 542 58161 D144 I M L G T Y F D K R R P L A N
Frog Xenopus laevis Q6GM59 460 50319 G122 L G V L T G L G F A L C Y S P
Zebra Danio Brachydanio rerio Q503M4 477 51835 C139 A M V G I Y F C E R K A L A Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97 88.8 N.A. 86.1 84.8 N.A. 80.5 39.4 30.3 32.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 98.5 94.4 N.A. 90.8 91.1 N.A. 89.6 58.2 50 49.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 73.3 0 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 80 13.3 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 10 0 10 0 90 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 90 10 10 0 0 0 0 0 0 % F
% Gly: 0 10 0 90 0 10 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 70 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 70 0 0 0 80 30 10 0 0 0 0 % K
% Leu: 10 0 10 10 0 0 10 0 0 0 10 0 90 0 0 % L
% Met: 0 90 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 80 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 60 80 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % S
% Thr: 70 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 90 0 60 0 0 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _