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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0174
All Species:
9.09
Human Site:
S181
Identified Species:
16.67
UniProt:
P53990
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53990
NP_055576.2
364
39751
S181
N
V
P
Y
E
P
D
S
V
V
M
A
E
A
P
Chimpanzee
Pan troglodytes
XP_001151193
502
54591
D319
Y
N
V
P
Y
E
P
D
S
V
V
M
A
E
A
Rhesus Macaque
Macaca mulatta
XP_001105424
362
39442
P179
N
Y
N
V
P
Y
E
P
D
S
V
V
M
A
E
Dog
Lupus familis
XP_536798
366
39902
V183
P
Y
E
P
D
S
V
V
M
A
E
A
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX00
362
39450
P179
N
Y
N
V
P
Y
E
P
D
S
V
V
M
A
E
Rat
Rattus norvegicus
Q568Z6
366
39923
S181
N
V
P
Y
E
P
D
S
V
V
M
A
E
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414234
366
39721
S181
N
V
P
Y
E
P
D
S
V
V
M
A
E
A
P
Frog
Xenopus laevis
NP_001086654
354
38586
A170
E
R
Y
L
I
E
I
A
K
N
Y
N
V
P
Y
Zebra Danio
Brachydanio rerio
NP_997750
354
38941
K171
R
Y
L
I
E
I
A
K
N
Y
N
V
P
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648058
417
45626
P182
N
I
E
Y
E
P
D
P
Q
V
M
Q
E
D
Q
Honey Bee
Apis mellifera
XP_001122854
352
39998
I169
V
E
K
Y
L
I
E
I
A
K
N
Y
N
V
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786445
370
40218
P181
N
V
P
Y
V
P
S
P
M
A
F
N
G
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53843
298
34477
I116
I
R
S
L
I
Y
A
I
L
F
V
D
E
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.3
97.8
96.7
N.A.
95
94.8
N.A.
N.A.
87.6
73.9
72.2
N.A.
47.7
47.7
N.A.
48.1
Protein Similarity:
100
72.3
98.9
97.5
N.A.
96.4
96.4
N.A.
N.A.
91.8
78.5
76.6
N.A.
59.4
62
N.A.
62.1
P-Site Identity:
100
6.6
13.3
6.6
N.A.
13.3
100
N.A.
N.A.
100
0
6.6
N.A.
53.3
6.6
N.A.
33.3
P-Site Similarity:
100
13.3
26.6
20
N.A.
26.6
100
N.A.
N.A.
100
6.6
6.6
N.A.
60
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
16
8
8
16
0
31
8
39
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
31
8
16
0
0
8
0
8
8
% D
% Glu:
8
8
16
0
39
16
24
0
0
0
8
0
39
16
31
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
8
16
16
8
16
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
8
8
0
0
0
0
8
% K
% Leu:
0
0
8
16
8
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
16
0
31
8
16
0
0
% M
% Asn:
54
8
16
0
0
0
0
0
8
8
16
16
8
0
0
% N
% Pro:
8
0
31
16
16
39
8
31
0
0
0
0
16
16
24
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% Q
% Arg:
8
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
8
8
24
8
16
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
31
8
16
8
0
8
8
24
39
31
24
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
31
8
47
8
24
0
0
0
8
8
8
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _