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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0174
All Species:
10.91
Human Site:
T218
Identified Species:
20
UniProt:
P53990
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53990
NP_055576.2
364
39751
T218
R
G
G
S
G
G
F
T
A
P
V
G
G
P
D
Chimpanzee
Pan troglodytes
XP_001151193
502
54591
T356
G
R
G
G
G
G
F
T
A
P
V
G
G
P
D
Rhesus Macaque
Macaca mulatta
XP_001105424
362
39442
G216
P
G
R
G
G
G
G
G
F
I
A
P
V
G
G
Dog
Lupus familis
XP_536798
366
39902
P220
G
G
G
G
F
T
A
P
V
G
G
P
D
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX00
362
39450
G216
P
G
R
G
G
G
G
G
F
T
A
P
V
G
G
Rat
Rattus norvegicus
Q568Z6
366
39923
T218
R
G
G
G
G
G
F
T
A
P
V
G
A
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414234
366
39721
T218
G
G
G
G
G
G
F
T
A
P
L
V
G
L
D
Frog
Xenopus laevis
NP_001086654
354
38586
G207
F
T
D
D
G
K
K
G
G
S
G
G
G
F
G
Zebra Danio
Brachydanio rerio
NP_997750
354
38941
G208
D
F
K
K
P
G
A
G
G
G
G
G
G
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648058
417
45626
Q219
G
G
G
A
A
P
P
Q
M
G
F
I
G
Y
P
Honey Bee
Apis mellifera
XP_001122854
352
39998
I206
T
E
R
N
N
L
D
I
A
S
G
G
I
T
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786445
370
40218
G218
S
G
G
G
G
G
G
G
G
G
M
P
V
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53843
298
34477
E153
A
D
H
I
D
V
P
E
K
I
I
K
K
C
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.3
97.8
96.7
N.A.
95
94.8
N.A.
N.A.
87.6
73.9
72.2
N.A.
47.7
47.7
N.A.
48.1
Protein Similarity:
100
72.3
98.9
97.5
N.A.
96.4
96.4
N.A.
N.A.
91.8
78.5
76.6
N.A.
59.4
62
N.A.
62.1
P-Site Identity:
100
80
20
13.3
N.A.
20
86.6
N.A.
N.A.
66.6
20
20
N.A.
20
13.3
N.A.
26.6
P-Site Similarity:
100
80
20
13.3
N.A.
20
86.6
N.A.
N.A.
73.3
20
20
N.A.
26.6
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
16
0
39
0
16
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
8
8
8
8
0
8
0
0
0
0
0
8
0
31
% D
% Glu:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
8
0
31
0
16
0
8
0
0
8
0
% F
% Gly:
31
62
54
54
62
62
24
39
24
31
31
47
47
31
31
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
16
8
8
8
0
8
% I
% Lys:
0
0
8
8
0
8
8
0
8
0
0
8
8
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
16
0
0
0
8
8
16
8
0
31
0
31
0
24
8
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% Q
% Arg:
16
8
24
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
0
0
0
0
0
16
0
0
0
0
8
% S
% Thr:
8
8
0
0
0
8
0
31
0
8
0
0
0
8
8
% T
% Val:
0
0
0
0
0
8
0
0
8
0
24
8
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _