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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0174
All Species:
13.64
Human Site:
T276
Identified Species:
25
UniProt:
P53990
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53990
NP_055576.2
364
39751
T276
H
P
P
Q
I
P
A
T
P
P
S
Y
E
S
V
Chimpanzee
Pan troglodytes
XP_001151193
502
54591
T414
H
P
P
Q
I
P
A
T
P
P
S
Y
E
S
V
Rhesus Macaque
Macaca mulatta
XP_001105424
362
39442
T274
H
P
P
Q
I
P
A
T
P
P
S
Y
E
S
V
Dog
Lupus familis
XP_536798
366
39902
T278
H
P
P
Q
I
P
A
T
P
P
S
Y
E
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX00
362
39450
P274
N
I
H
P
P
Q
I
P
A
T
P
P
S
Y
E
Rat
Rattus norvegicus
Q568Z6
366
39923
Q276
F
P
N
I
H
P
P
Q
I
P
A
T
P
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414234
366
39721
P276
N
I
H
P
P
P
I
P
A
N
P
P
T
Y
E
Frog
Xenopus laevis
NP_001086654
354
38586
P265
N
P
A
V
G
G
V
P
P
P
V
P
S
M
P
Zebra Danio
Brachydanio rerio
NP_997750
354
38941
M266
F
S
N
F
Q
A
P
M
R
G
G
Q
P
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648058
417
45626
A277
V
Q
A
P
P
P
F
A
Y
N
I
P
P
N
Q
Honey Bee
Apis mellifera
XP_001122854
352
39998
I264
P
S
N
V
L
Y
N
I
P
L
D
N
S
N
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786445
370
40218
P276
G
Y
P
Q
M
P
N
P
L
P
P
S
V
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53843
298
34477
D211
D
P
S
G
D
I
E
D
N
D
E
E
K
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.3
97.8
96.7
N.A.
95
94.8
N.A.
N.A.
87.6
73.9
72.2
N.A.
47.7
47.7
N.A.
48.1
Protein Similarity:
100
72.3
98.9
97.5
N.A.
96.4
96.4
N.A.
N.A.
91.8
78.5
76.6
N.A.
59.4
62
N.A.
62.1
P-Site Identity:
100
100
100
100
N.A.
0
20
N.A.
N.A.
6.6
20
0
N.A.
6.6
6.6
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
6.6
26.6
N.A.
N.A.
13.3
26.6
0
N.A.
13.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
8
31
8
16
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
8
0
8
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
8
8
31
0
16
% E
% Phe:
16
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
8
8
0
0
0
8
8
0
0
0
8
% G
% His:
31
0
16
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
8
31
8
16
8
8
0
8
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
8
8
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
24
0
24
0
0
0
16
0
8
16
0
8
0
16
0
% N
% Pro:
8
54
39
24
24
62
16
31
47
54
24
31
24
31
8
% P
% Gln:
0
8
0
39
8
8
0
8
0
0
0
8
0
0
16
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
16
8
0
0
0
0
0
0
0
31
8
24
31
8
% S
% Thr:
0
0
0
0
0
0
0
31
0
8
0
8
8
0
0
% T
% Val:
8
0
0
16
0
0
8
0
0
0
8
0
8
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
0
8
0
0
31
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _