KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0174
All Species:
20.91
Human Site:
Y318
Identified Species:
38.33
UniProt:
P53990
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53990
NP_055576.2
364
39751
Y318
P
S
R
P
A
D
N
Y
D
N
F
V
L
P
E
Chimpanzee
Pan troglodytes
XP_001151193
502
54591
Y456
P
S
R
P
A
D
N
Y
D
N
F
V
L
P
E
Rhesus Macaque
Macaca mulatta
XP_001105424
362
39442
Y316
P
S
R
P
A
D
N
Y
D
N
F
V
L
P
E
Dog
Lupus familis
XP_536798
366
39902
Y320
P
S
R
P
V
D
T
Y
D
N
F
V
L
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX00
362
39450
Y316
P
S
R
P
V
D
N
Y
N
T
F
V
L
P
E
Rat
Rattus norvegicus
Q568Z6
366
39923
D318
K
P
P
S
R
P
V
D
N
Y
N
T
F
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414234
366
39721
N318
K
P
R
V
G
P
P
N
T
I
D
N
F
V
L
Frog
Xenopus laevis
NP_001086654
354
38586
T307
V
A
K
P
R
T
K
T
P
D
N
F
V
L
P
Zebra Danio
Brachydanio rerio
NP_997750
354
38941
Y308
P
T
P
A
G
Q
V
Y
D
N
S
T
L
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648058
417
45626
P319
N
T
D
G
S
G
S
P
D
E
N
I
L
R
P
Honey Bee
Apis mellifera
XP_001122854
352
39998
M306
K
P
Q
P
R
S
K
M
P
M
N
D
F
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786445
370
40218
T318
M
P
P
S
Q
P
P
T
S
Q
L
P
S
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53843
298
34477
I253
N
I
K
N
E
L
K
I
P
K
D
I
K
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.3
97.8
96.7
N.A.
95
94.8
N.A.
N.A.
87.6
73.9
72.2
N.A.
47.7
47.7
N.A.
48.1
Protein Similarity:
100
72.3
98.9
97.5
N.A.
96.4
96.4
N.A.
N.A.
91.8
78.5
76.6
N.A.
59.4
62
N.A.
62.1
P-Site Identity:
100
100
100
86.6
N.A.
80
0
N.A.
N.A.
6.6
6.6
46.6
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
6.6
N.A.
N.A.
6.6
33.3
53.3
N.A.
40
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
24
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
39
0
8
47
8
16
8
0
8
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
54
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
39
8
24
0
0
% F
% Gly:
0
0
0
8
16
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
8
0
16
0
0
0
% I
% Lys:
24
0
16
0
0
0
24
0
0
8
0
0
8
8
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
8
0
54
8
24
% L
% Met:
8
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
16
0
0
8
0
0
31
8
16
39
31
8
0
0
0
% N
% Pro:
47
31
24
54
0
24
16
8
24
0
0
8
0
47
16
% P
% Gln:
0
0
8
0
8
8
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
47
0
24
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
39
0
16
8
8
8
0
8
0
8
0
8
0
8
% S
% Thr:
0
16
0
0
0
8
8
16
8
8
0
16
0
0
0
% T
% Val:
8
0
0
8
16
0
16
0
0
0
0
39
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _