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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0174 All Species: 27.27
Human Site: Y64 Identified Species: 50
UniProt: P53990 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53990 NP_055576.2 364 39751 Y64 E H I I R E D Y L V E A M E I
Chimpanzee Pan troglodytes XP_001151193 502 54591 Y203 E H I I R E D Y L V E A M E I
Rhesus Macaque Macaca mulatta XP_001105424 362 39442 H58 R A R I R V E H I I R E D Y L
Dog Lupus familis XP_536798 366 39902 Y64 E H I I R E D Y L V E A M E I
Cat Felis silvestris
Mouse Mus musculus Q9CX00 362 39450 H58 R A R I R V E H I I R E D Y L
Rat Rattus norvegicus Q568Z6 366 39923 Y64 E H I I R E D Y L V E A M E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414234 366 39721 Y64 E H I I R E D Y L V E A M E I
Frog Xenopus laevis NP_001086654 354 38586 E50 Y L S T G K D E R A R I R V E
Zebra Danio Brachydanio rerio NP_997750 354 38941 E50 Y L S A G K D E R A R I R V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648058 417 45626 Y64 E H I I R E D Y L V E A M E M
Honey Bee Apis mellifera XP_001122854 352 39998 E50 Y L A A G K I E R A K I R V E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786445 370 40218 Y64 E H I I R E D Y L V E A M E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53843 298 34477
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.3 97.8 96.7 N.A. 95 94.8 N.A. N.A. 87.6 73.9 72.2 N.A. 47.7 47.7 N.A. 48.1
Protein Similarity: 100 72.3 98.9 97.5 N.A. 96.4 96.4 N.A. N.A. 91.8 78.5 76.6 N.A. 59.4 62 N.A. 62.1
P-Site Identity: 100 100 13.3 100 N.A. 13.3 100 N.A. N.A. 100 6.6 6.6 N.A. 93.3 0 N.A. 93.3
P-Site Similarity: 100 100 46.6 100 N.A. 46.6 100 N.A. N.A. 100 13.3 13.3 N.A. 100 13.3 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 8 16 0 0 0 0 0 24 0 54 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 70 0 0 0 0 0 16 0 0 % D
% Glu: 54 0 0 0 0 54 16 24 0 0 54 16 0 54 24 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 24 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 54 0 0 0 0 0 16 0 0 0 0 0 0 0 % H
% Ile: 0 0 54 70 0 0 8 0 16 16 0 24 0 0 39 % I
% Lys: 0 0 0 0 0 24 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 24 0 0 0 0 0 0 54 0 0 0 0 0 24 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 54 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 16 0 16 0 70 0 0 0 24 0 31 0 24 0 0 % R
% Ser: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 16 0 0 0 54 0 0 0 24 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 24 0 0 0 0 0 0 54 0 0 0 0 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _