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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 16.97
Human Site: S191 Identified Species: 26.67
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 S191 Q G Q A P P L S Q A Q G H P G
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S191 Q G Q A P P L S Q A Q G H P G
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 P162 S S G L G Y G P P T S L A S A
Dog Lupus familis XP_850963 1096 118584 S192 Q G Q A P P L S Q A Q G H L G
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 Q194 P G S A L P L Q N P P L P P T
Rat Rattus norvegicus NP_001102926 1095 118506 S191 Q S Q A P P L S Q A Q G H P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 T192 T P P L P P L T V Q N R I P G
Chicken Gallus gallus XP_421617 1147 124543 R248 G Q P V P T Q R L P T E V P G
Frog Xenopus laevis NP_001087832 1126 123503 T191 G P S P I N L T Q G M P P T S
Zebra Danio Brachydanio rerio XP_700597 1315 142554 A191 S M Q V G S T A P S P A G P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 S301 G Q N L I G P S L S K Q N L S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 P234 S G F Q G Q P P T G F A S G P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 V200 V S N G H Q M V G S G G F P R
Baker's Yeast Sacchar. cerevisiae P53953 876 98925 M40 I D Q T A Y A M G N L Q L N N
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 G114 G A P T T P Y G A P Q P A V P
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 0 93.3 N.A. 33.3 93.3 N.A. 33.3 20 13.3 20 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 0 93.3 N.A. 33.3 93.3 N.A. 40 20 20 33.3 N.A. N.A. 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 34 7 0 7 7 7 27 0 14 14 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 7 0 7 0 0 % F
% Gly: 27 34 7 7 20 7 7 7 14 14 7 34 7 7 47 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 27 0 0 % H
% Ile: 7 0 0 0 14 0 0 0 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % K
% Leu: 0 0 0 20 7 0 47 0 14 0 7 14 7 14 0 % L
% Met: 0 7 0 0 0 0 7 7 0 0 7 0 0 0 0 % M
% Asn: 0 0 14 0 0 7 0 0 7 7 7 0 7 7 7 % N
% Pro: 7 14 20 7 40 47 14 14 14 20 14 14 14 54 14 % P
% Gln: 27 14 40 7 0 14 7 7 34 7 34 14 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 7 % R
% Ser: 20 20 14 0 0 7 0 34 0 20 7 0 7 7 14 % S
% Thr: 7 0 0 14 7 7 7 14 7 7 7 0 0 7 7 % T
% Val: 7 0 0 14 0 0 0 7 7 0 0 0 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 14 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _