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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 8.48
Human Site: S65 Identified Species: 13.33
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 S65 G M S R A P P S S G A P P A S
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S65 G M S R A P P S S G A P P A S
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 A36 G G Q S G S T A P T I P Y G A
Dog Lupus familis XP_850963 1096 118584 S66 V S R A P P S S E A P P A S T
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 N68 P M P A K T L N P F S A Q S N
Rat Rattus norvegicus NP_001102926 1095 118506 C65 G V P R A P P C S G A P P A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 I66 G P G P Q P L I Q N G P P G S
Chicken Gallus gallus XP_421617 1147 124543 Q122 Q F G Q G D V Q N G I P T S T
Frog Xenopus laevis NP_001087832 1126 123503 P65 P P P V S T A P T P T I A G S
Zebra Danio Brachydanio rerio XP_700597 1315 142554 S65 A P D N G P G S G Y Q Q G P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 P175 T T L K T S T P Q L T G L P F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 Q108 P M G G Y P A Q G Q R P P G P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 S74 P F P Q Q S P S Y G A P Q R G
Baker's Yeast Sacchar. cerevisiae P53953 876 98925
Red Bread Mold Neurospora crassa Q7S4P3 950 103512
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 13.3 20 N.A. 6.6 80 N.A. 33.3 13.3 6.6 13.3 N.A. N.A. 0 N.A. 26.6
P-Site Similarity: 100 100 26.6 33.3 N.A. 33.3 86.6 N.A. 33.3 40 20 13.3 N.A. N.A. 6.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 33.3 0 0
P-Site Similarity: N.A. N.A. N.A. 40 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 14 20 0 14 7 0 7 27 7 14 20 7 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % E
% Phe: 0 14 0 0 0 0 0 0 0 7 0 0 0 0 7 % F
% Gly: 34 7 20 7 20 0 7 0 14 34 7 7 7 27 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 14 7 0 0 0 % I
% Lys: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 7 0 0 0 14 0 0 7 0 0 7 0 0 % L
% Met: 0 27 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 7 7 7 0 0 0 0 7 % N
% Pro: 27 20 27 7 7 47 27 14 14 7 7 60 34 14 14 % P
% Gln: 7 0 7 14 14 0 0 14 14 7 7 7 14 0 0 % Q
% Arg: 0 0 7 20 0 0 0 0 0 0 7 0 0 7 0 % R
% Ser: 0 7 14 7 7 20 7 34 20 0 7 0 0 20 34 % S
% Thr: 7 7 0 0 7 14 14 0 7 7 14 0 7 0 14 % T
% Val: 7 7 0 7 0 0 7 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 7 7 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _