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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 12.12
Human Site: S97 Identified Species: 19.05
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 S97 D V Q N G P S S T V Q M Q R L
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S97 D V Q N G P S S T V Q M Q R L
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 A68 R A P P S S G A P P A S T A Q
Dog Lupus familis XP_850963 1096 118584 T98 V Q N G P S S T V Q M Q R F P
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 L100 S G P V L P S L H S G P V P R
Rat Rattus norvegicus NP_001102926 1095 118506 S97 D I Q N G P S S T A Q M P R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 H98 F A G P P F S H P S Q P P Y P
Chicken Gallus gallus XP_421617 1147 124543 S154 P A P V S Q P S T F Q Q Y G P
Frog Xenopus laevis NP_001087832 1126 123503 A97 H N G P T S V A N Q M Q R P P
Zebra Danio Brachydanio rerio XP_700597 1315 142554 S97 L V S D L S S S S P L D L G M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 N207 L P T E Q V F N A G M P S N Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 Q140 P P Q G Q P Q Q N L P G S Y G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 P106 G P P P V S Q P A G F Q S N V
Baker's Yeast Sacchar. cerevisiae P53953 876 98925
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 E20 Y P P Q Q Y G E Q P Q Y P V E
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 0 6.6 N.A. 13.3 73.3 N.A. 13.3 20 0 20 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 6.6 20 N.A. 13.3 86.6 N.A. 13.3 20 13.3 40 N.A. N.A. 6.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 0 0 6.6
P-Site Similarity: N.A. N.A. N.A. 6.6 0 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 0 0 0 14 14 7 7 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 0 7 0 0 0 0 0 0 0 7 0 0 0 % D
% Glu: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 7 % E
% Phe: 7 0 0 0 0 7 7 0 0 7 7 0 0 7 0 % F
% Gly: 7 7 14 14 20 0 14 0 0 14 7 7 0 14 7 % G
% His: 7 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 14 0 0 0 14 0 0 7 0 7 7 0 7 0 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 20 20 0 0 7 % M
% Asn: 0 7 7 20 0 0 0 7 14 0 0 0 0 14 0 % N
% Pro: 14 27 34 27 14 34 7 7 14 20 7 20 20 14 27 % P
% Gln: 0 7 27 7 20 7 14 7 7 14 40 27 14 0 14 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 0 0 14 20 7 % R
% Ser: 7 0 7 0 14 34 47 34 7 14 0 7 20 0 0 % S
% Thr: 0 0 7 0 7 0 0 7 27 0 0 0 7 0 0 % T
% Val: 7 20 0 14 7 7 7 0 7 14 0 0 7 7 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 7 0 0 0 0 0 7 7 14 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _