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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 30.61
Human Site: S976 Identified Species: 48.1
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 S976 R A S E E R L S N G D I Y L L
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S976 R A S E E R L S N G D I Y L L
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 L888 F Y P R L L P L T K S P I E S
Dog Lupus familis XP_850963 1096 118584 S978 R A S E E R L S N G D I Y L L
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 S976 Q L S V E K L S R D G A F L M
Rat Rattus norvegicus NP_001102926 1095 118506 S977 R A S E E R L S S G D I Y L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 A920 E G G V F L L A N G L H M F L
Chicken Gallus gallus XP_421617 1147 124543 S1029 R N S E E R L S K G D I Y L L
Frog Xenopus laevis NP_001087832 1126 123503 S1008 R S S E E R L S K G E V Y L L
Zebra Danio Brachydanio rerio XP_700597 1315 142554 G1199 S E E R L S R G G V Y L L E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 T1157 R C S I D K F T D D G A Y L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 E1032 R C S I E R F E D Q G V Y I L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 S964 P L S G E H I S N E G V Y F L
Baker's Yeast Sacchar. cerevisiae P53953 876 98925 A766 F L W V G G D A V P E L L I D
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 T840 Y L I D D G Q T Q F L W V G R
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 0 100 N.A. 33.3 93.3 N.A. 26.6 86.6 73.3 0 N.A. N.A. 33.3 N.A. 40
P-Site Similarity: 100 100 0 100 N.A. 60 100 N.A. 33.3 86.6 93.3 6.6 N.A. N.A. 60 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 40 0 0
P-Site Similarity: N.A. N.A. N.A. 53.3 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 27 0 0 0 0 0 14 0 0 0 14 0 0 0 % A
% Cys: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 14 0 7 0 14 14 34 0 0 0 7 % D
% Glu: 7 7 7 40 60 0 0 7 0 7 14 0 0 14 0 % E
% Phe: 14 0 0 0 7 0 14 0 0 7 0 0 7 14 0 % F
% Gly: 0 7 7 7 7 14 0 7 7 47 27 0 0 7 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 7 14 0 0 7 0 0 0 0 34 7 14 0 % I
% Lys: 0 0 0 0 0 14 0 0 14 7 0 0 0 0 0 % K
% Leu: 0 27 0 0 14 14 54 7 0 0 14 14 14 54 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % M
% Asn: 0 7 0 0 0 0 0 0 34 0 0 0 0 0 7 % N
% Pro: 7 0 7 0 0 0 7 0 0 7 0 7 0 0 0 % P
% Gln: 7 0 0 0 0 0 7 0 7 7 0 0 0 0 0 % Q
% Arg: 54 0 0 14 0 47 7 0 7 0 0 0 0 0 7 % R
% Ser: 7 7 67 0 0 7 0 54 7 0 7 0 0 0 7 % S
% Thr: 0 0 0 0 0 0 0 14 7 0 0 0 0 0 0 % T
% Val: 0 0 0 20 0 0 0 0 7 7 0 20 7 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 7 7 0 0 0 0 0 0 0 0 7 0 60 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _