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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 16.97
Human Site: T963 Identified Species: 26.67
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 T963 K S P V E S T T E P P A V R A
Chimpanzee Pan troglodytes XP_001145058 1094 118246 T963 K S P V E S T T E P P A V R A
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 A875 L V T S M D V A E T N V F F Y
Dog Lupus familis XP_850963 1096 118584 T965 K S P I E S A T E P P A V R A
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 P963 N I N D R T I P Q P P I L Q L
Rat Rattus norvegicus NP_001102926 1095 118506 T964 K S P L D S T T E P P A V R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 S907 F P T A V R C S E E R L S E G
Chicken Gallus gallus XP_421617 1147 124543 S1016 K A D V D S D S L P A A I R N
Frog Xenopus laevis NP_001087832 1126 123503 G995 K M D P S N D G L P L A I R S
Zebra Danio Brachydanio rerio XP_700597 1315 142554 P1186 D A E S T S L P L A V R D S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 E1144 D V D L Q D T E L P Q M L R C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 D1019 D I D V N S E D T P A A V R C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 V951 V K D T E G S V L P P P I P L
Baker's Yeast Sacchar. cerevisiae P53953 876 98925 D753 R Y G L Y L I D N S A E L F L
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 F827 M N L S S E R F V P F G L Y L
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 6.6 86.6 N.A. 13.3 86.6 N.A. 6.6 40 26.6 6.6 N.A. N.A. 20 N.A. 40
P-Site Similarity: 100 100 6.6 93.3 N.A. 40 100 N.A. 13.3 66.6 46.6 13.3 N.A. N.A. 40 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 20 0 6.6
P-Site Similarity: N.A. N.A. N.A. 33.3 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 7 0 0 7 7 0 7 20 47 0 0 27 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 14 % C
% Asp: 20 0 34 7 14 14 14 14 0 0 0 0 7 0 0 % D
% Glu: 0 0 7 0 27 7 7 7 40 7 0 7 0 7 7 % E
% Phe: 7 0 0 0 0 0 0 7 0 0 7 0 7 14 0 % F
% Gly: 0 0 7 0 0 7 0 7 0 0 0 7 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 14 0 7 0 0 14 0 0 0 0 7 20 0 0 % I
% Lys: 40 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 7 20 0 7 7 0 34 0 7 7 27 0 27 % L
% Met: 7 7 0 0 7 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 7 7 7 0 7 7 0 0 7 0 7 0 0 0 7 % N
% Pro: 0 7 27 7 0 0 0 14 0 74 40 7 0 7 0 % P
% Gln: 0 0 0 0 7 0 0 0 7 0 7 0 0 7 0 % Q
% Arg: 7 0 0 0 7 7 7 0 0 0 7 7 0 54 0 % R
% Ser: 0 27 0 20 14 47 7 14 0 7 0 0 7 7 7 % S
% Thr: 0 0 14 7 7 7 27 27 7 7 0 0 0 0 0 % T
% Val: 7 14 0 27 7 0 7 7 7 0 7 7 34 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 0 0 0 0 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _