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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 12.42
Human Site: Y51 Identified Species: 19.52
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 Y51 Y N G P V P G Y Q Q T P P Q G
Chimpanzee Pan troglodytes XP_001145058 1094 118246 Y51 Y N G P V P G Y Q Q T P P Q G
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 G22 Q P Q P V Y P G Y H Q S S Y G
Dog Lupus familis XP_850963 1096 118584 Q52 N G P V P G Y Q Q T S P P G V
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 P54 S Q G Y D S Q P P G S Y P R P
Rat Rattus norvegicus NP_001102926 1095 118506 Y51 Y N G P V P G Y Q Q A P P Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 T52 P A G P V G A T A P I G S P G
Chicken Gallus gallus XP_421617 1147 124543 S108 A S G T S L P S G H Q G Y S Q
Frog Xenopus laevis NP_001087832 1126 123503 P51 Q G Y S Q H D P T Q G L M G P
Zebra Danio Brachydanio rerio XP_700597 1315 142554 S51 Y G G G H V P S G Y P A Q Y A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 T161 S G P P I S G T N V Q E Q K T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 N94 P P P G P G S N Q F G A P R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 P60 S G P R P P P P F G Q S P Q P
Baker's Yeast Sacchar. cerevisiae P53953 876 98925
Red Bread Mold Neurospora crassa Q7S4P3 950 103512
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 20 20 N.A. 13.3 93.3 N.A. 26.6 6.6 6.6 13.3 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 100 20 26.6 N.A. 26.6 93.3 N.A. 26.6 13.3 6.6 13.3 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 20 0 0
P-Site Similarity: N.A. N.A. N.A. 20 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 0 0 7 0 7 0 7 14 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % F
% Gly: 0 34 47 14 0 20 27 7 14 14 14 14 0 14 34 % G
% His: 0 0 0 0 7 7 0 0 0 14 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % K
% Leu: 0 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 7 20 0 0 0 0 0 7 7 0 0 0 0 0 0 % N
% Pro: 14 14 27 40 20 27 27 20 7 7 7 27 47 7 27 % P
% Gln: 14 7 7 0 7 0 7 7 34 27 27 0 14 27 7 % Q
% Arg: 0 0 0 7 0 0 0 0 0 0 0 0 0 14 0 % R
% Ser: 20 7 0 7 7 14 7 14 0 0 14 14 14 7 0 % S
% Thr: 0 0 0 7 0 0 0 14 7 7 14 0 0 0 7 % T
% Val: 0 0 0 7 34 7 0 0 0 7 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 27 0 7 7 0 7 7 20 7 7 0 7 7 14 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _