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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUB1 All Species: 38.48
Human Site: S12 Identified Species: 60.48
UniProt: P53999 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53999 NP_006704.3 127 14395 S12 K E L V S S S S S G S D S D S
Chimpanzee Pan troglodytes XP_001154452 153 17638 S38 K E L V S S S S S G S D S D S
Rhesus Macaque Macaca mulatta XP_001089347 166 18812 S53 K E L V S S S S S G S D S D S
Dog Lupus familis XP_536425 318 35815 S203 K E L V S S S S S G S D S D S
Cat Felis silvestris
Mouse Mus musculus P11031 127 14409 S12 K E L V S S S S S G S D S D S
Rat Rattus norvegicus Q63396 127 14423 S12 K E L V S S S S S G S D S D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521441 125 14064 S12 K E L V S S S S S G S D S D S
Chicken Gallus gallus Q5ZK63 126 14219 S12 K E L V S S S S S A S D S D S
Frog Xenopus laevis NP_001084564 128 14361 S12 K E I L S S S S S G S D S D S
Zebra Danio Brachydanio rerio NP_001002505 124 13869 S12 K E V L S S T S G S E S D G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLR5 110 12170
Honey Bee Apis mellifera XP_624593 119 13804 D12 K E Y V S T D D D S S D E G M
Nematode Worm Caenorhab. elegans Q94045 124 14428 Q19 E K K V T K E Q K K K E T K S
Sea Urchin Strong. purpuratus XP_001177085 115 13090 Q11 H K S K E T L Q A S S S S E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65154 107 12065
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83 67.4 39.6 N.A. 93.6 93.6 N.A. 91.3 89.7 79.6 70.8 N.A. 32.2 41.7 33 39.3
Protein Similarity: 100 83 72.2 39.6 N.A. 96 96.8 N.A. 93.6 94.4 91.4 85 N.A. 51.9 62.9 51.9 59
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 86.6 33.3 N.A. 0 40 13.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 100 53.3 N.A. 0 46.6 46.6 40
Percent
Protein Identity: N.A. N.A. N.A. 33 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 7 7 0 0 67 7 60 14 % D
% Glu: 7 74 0 0 7 0 7 0 0 0 7 7 7 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 7 54 0 0 0 14 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 74 14 7 7 0 7 0 0 7 7 7 0 0 7 0 % K
% Leu: 0 0 54 14 0 0 7 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 0 74 67 60 67 60 20 74 14 67 0 67 % S
% Thr: 0 0 0 0 7 14 7 0 0 0 0 0 7 0 0 % T
% Val: 0 0 7 67 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _