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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUB1 All Species: 38.48
Human Site: S19 Identified Species: 60.48
UniProt: P53999 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53999 NP_006704.3 127 14395 S19 S S G S D S D S E V D K K L K
Chimpanzee Pan troglodytes XP_001154452 153 17638 S45 S S G S D S D S E V D K K L K
Rhesus Macaque Macaca mulatta XP_001089347 166 18812 S60 S S G S D S D S E V D K K R K
Dog Lupus familis XP_536425 318 35815 S210 S S G S D S D S E V D K K L K
Cat Felis silvestris
Mouse Mus musculus P11031 127 14409 S19 S S G S D S D S E V E K K L K
Rat Rattus norvegicus Q63396 127 14423 S19 S S G S D S D S E V E K K L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521441 125 14064 S19 S S G S D S D S E V D K K A K
Chicken Gallus gallus Q5ZK63 126 14219 S19 S S A S D S D S E V D K K A K
Frog Xenopus laevis NP_001084564 128 14361 S19 S S G S D S D S E V D Q K V K
Zebra Danio Brachydanio rerio NP_001002505 124 13869 D19 S G S E S D G D A E T K V K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLR5 110 12170 S13 K K D S S S D S D S G P D D R
Honey Bee Apis mellifera XP_624593 119 13804 M19 D D S S D E G M K P K K K Q K
Nematode Worm Caenorhab. elegans Q94045 124 14428 S26 Q K K K E T K S K K R Q S E A
Sea Urchin Strong. purpuratus XP_001177085 115 13090 D18 Q A S S S S E D E P T P K R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65154 107 12065 E10 S R G K R K D E D V R A S D D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83 67.4 39.6 N.A. 93.6 93.6 N.A. 91.3 89.7 79.6 70.8 N.A. 32.2 41.7 33 39.3
Protein Similarity: 100 83 72.2 39.6 N.A. 96 96.8 N.A. 93.6 94.4 91.4 85 N.A. 51.9 62.9 51.9 59
P-Site Identity: 100 100 93.3 100 N.A. 93.3 93.3 N.A. 93.3 86.6 86.6 13.3 N.A. 26.6 33.3 6.6 26.6
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 93.3 86.6 100 20 N.A. 40 40 33.3 40
Percent
Protein Identity: N.A. N.A. N.A. 33 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 0 0 0 7 0 0 7 0 14 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 7 0 67 7 74 14 14 0 47 0 7 14 7 % D
% Glu: 0 0 0 7 7 7 7 7 67 7 14 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 60 0 0 0 14 0 0 0 7 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 14 7 14 0 7 7 0 14 7 7 67 74 7 67 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 14 0 14 0 0 0 % P
% Gln: 14 0 0 0 0 0 0 0 0 0 0 14 0 7 0 % Q
% Arg: 0 7 0 0 7 0 0 0 0 0 14 0 0 14 14 % R
% Ser: 74 60 20 80 20 74 0 74 0 7 0 0 14 0 7 % S
% Thr: 0 0 0 0 0 7 0 0 0 0 14 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 67 0 0 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _