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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLG
All Species:
27.27
Human Site:
S1021
Identified Species:
50
UniProt:
P54098
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54098
NP_001119603.1
1239
139562
S1021
R
T
E
G
G
W
I
S
L
Q
D
L
R
K
V
Chimpanzee
Pan troglodytes
XP_523149
1236
139116
S1018
R
T
E
G
G
W
I
S
L
Q
D
L
R
K
V
Rhesus Macaque
Macaca mulatta
XP_001092360
1228
138042
S1010
R
T
E
G
G
W
I
S
L
Q
D
L
R
K
V
Dog
Lupus familis
XP_545850
1234
138197
S1022
R
T
E
D
G
W
V
S
L
Q
D
L
R
K
I
Cat
Felis silvestris
Mouse
Mus musculus
P54099
1239
138880
S1000
R
T
E
D
G
W
V
S
L
Q
D
L
R
M
I
Rat
Rattus norvegicus
Q9QYV8
1216
136837
S998
R
T
E
D
G
W
V
S
L
Q
D
L
R
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92076
647
72836
Q441
A
Q
D
V
Q
K
I
Q
R
E
A
M
R
K
S
Frog
Xenopus laevis
Q91684
1200
137225
N991
R
G
E
E
N
S
V
N
L
Q
D
L
R
K
I
Zebra Danio
Brachydanio rerio
XP_001921328
1203
137518
S982
R
A
E
D
G
S
I
S
L
Q
D
L
R
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27607
1145
129809
A933
R
A
Y
S
S
Y
E
A
S
R
L
A
I
Q
R
Honey Bee
Apis mellifera
XP_395230
1086
125181
A880
K
L
Y
S
S
Y
E
A
Y
K
L
S
K
L
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15801
1254
143484
A1022
E
F
L
K
Y
F
L
A
M
Q
V
Q
S
D
K
Red Bread Mold
Neurospora crassa
Q9Y767
1456
161685
S1084
I
R
A
Q
I
T
N
S
D
E
E
L
K
R
I
Conservation
Percent
Protein Identity:
100
99.1
96.4
87.8
N.A.
85.4
85.6
N.A.
N.A.
41.6
64.8
67.1
N.A.
42.7
39.7
N.A.
N.A.
Protein Similarity:
100
99.3
97.3
91.1
N.A.
89.5
90.3
N.A.
N.A.
47
77
77.6
N.A.
57.8
57.7
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
73.3
80
N.A.
N.A.
20
53.3
73.3
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
40
73.3
80
N.A.
33.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
21.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
38.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
0
0
0
0
24
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
31
0
0
0
0
8
0
62
0
0
8
0
% D
% Glu:
8
0
62
8
0
0
16
0
0
16
8
0
0
0
0
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
24
54
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
8
0
39
0
0
0
0
0
8
0
47
% I
% Lys:
8
0
0
8
0
8
0
0
0
8
0
0
16
62
8
% K
% Leu:
0
8
8
0
0
0
8
0
62
0
16
70
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
8
0
0
8
0
70
0
8
0
8
0
% Q
% Arg:
70
8
0
0
0
0
0
0
8
8
0
0
70
8
8
% R
% Ser:
0
0
0
16
16
16
0
62
8
0
0
8
8
0
8
% S
% Thr:
0
47
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
31
0
0
0
8
0
0
0
24
% V
% Trp:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
8
16
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _