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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLG
All Species:
15.15
Human Site:
S1235
Identified Species:
27.78
UniProt:
P54098
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54098
NP_001119603.1
1239
139562
S1235
K
G
S
L
E
K
R
S
Q
P
G
P
_
_
_
Chimpanzee
Pan troglodytes
XP_523149
1236
139116
S1232
K
G
S
L
E
K
R
S
Q
P
G
P
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001092360
1228
138042
S1224
K
G
S
L
E
K
R
S
Q
P
G
P
_
_
_
Dog
Lupus familis
XP_545850
1234
138197
G1230
Q
I
I
E
L
T
K
G
S
L
E
Q
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P54099
1239
138880
K1214
K
G
S
L
E
K
R
K
P
A
W
T
L
A
L
Rat
Rattus norvegicus
Q9QYV8
1216
136837
S1212
K
G
S
L
E
K
R
S
Q
P
G
P
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92076
647
72836
Frog
Xenopus laevis
Q91684
1200
137225
T1196
I
Y
Q
I
L
K
V
T
K
G
V
L
_
_
_
Zebra Danio
Brachydanio rerio
XP_001921328
1203
137518
K1196
K
G
S
L
T
K
E
K
R
Q
A
P
R
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27607
1145
129809
W1139
G
G
N
D
V
S
Q
W
D
W
I
K
K
S
_
Honey Bee
Apis mellifera
XP_395230
1086
125181
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15801
1254
143484
A1231
V
H
S
K
K
L
P
A
R
K
S
S
T
T
N
Red Bread Mold
Neurospora crassa
Q9Y767
1456
161685
K1397
L
P
S
S
A
F
S
K
E
Q
K
E
P
M
S
Conservation
Percent
Protein Identity:
100
99.1
96.4
87.8
N.A.
85.4
85.6
N.A.
N.A.
41.6
64.8
67.1
N.A.
42.7
39.7
N.A.
N.A.
Protein Similarity:
100
99.3
97.3
91.1
N.A.
89.5
90.3
N.A.
N.A.
47
77
77.6
N.A.
57.8
57.7
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
46.6
100
N.A.
N.A.
0
8.3
40
N.A.
7.1
0
N.A.
N.A.
P-Site Similarity:
100
100
100
16.6
N.A.
46.6
100
N.A.
N.A.
0
33.3
46.6
N.A.
21.4
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
21.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
38.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
8
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
39
0
8
0
8
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
54
0
0
0
0
0
8
0
8
31
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
8
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
47
0
0
8
8
54
8
24
8
8
8
8
8
0
8
% K
% Leu:
8
0
0
47
16
8
0
0
0
8
0
8
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
8
0
0
0
0
8
0
8
31
0
39
8
0
0
% P
% Gln:
8
0
8
0
0
0
8
0
31
16
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
39
0
16
0
0
0
8
0
0
% R
% Ser:
0
0
62
8
0
8
8
31
8
0
8
8
0
16
8
% S
% Thr:
0
0
0
0
8
8
0
8
0
0
0
8
8
8
0
% T
% Val:
8
0
0
0
8
0
8
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
47
47
54
% _