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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLG All Species: 31.52
Human Site: S809 Identified Species: 57.78
UniProt: P54098 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54098 NP_001119603.1 1239 139562 S809 R N A H K R I S S Q M V V W L
Chimpanzee Pan troglodytes XP_523149 1236 139116 S806 R N A H K R I S S Q M V V W L
Rhesus Macaque Macaca mulatta XP_001092360 1228 138042 S798 R N A H K R I S S Q M V V W L
Dog Lupus familis XP_545850 1234 138197 S810 R N A H K R I S S Q M V V W L
Cat Felis silvestris
Mouse Mus musculus P54099 1239 138880 S788 R N A H K R I S S Q M V V W L
Rat Rattus norvegicus Q9QYV8 1216 136837 S786 R N A H K R I S S Q M V V W L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q92076 647 72836 P241 P R A V T R H P A Y S E E E D
Frog Xenopus laevis Q91684 1200 137225 S779 R N A H K R I S S Q M V V W M
Zebra Danio Brachydanio rerio XP_001921328 1203 137518 S770 R N A Q K R I S S Q M V V W L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27607 1145 129809 R727 Y W R N N R D R I M G Q M V V
Honey Bee Apis mellifera XP_395230 1086 125181 I680 R I M S Q F T I W F E K S Y L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P15801 1254 143484 G808 F K K F W Y G G S E S I L F N
Red Bread Mold Neurospora crassa Q9Y767 1456 161685 G857 K R P F W R G G T E S F V F N
Conservation
Percent
Protein Identity: 100 99.1 96.4 87.8 N.A. 85.4 85.6 N.A. N.A. 41.6 64.8 67.1 N.A. 42.7 39.7 N.A. N.A.
Protein Similarity: 100 99.3 97.3 91.1 N.A. 89.5 90.3 N.A. N.A. 47 77 77.6 N.A. 57.8 57.7 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 13.3 93.3 93.3 N.A. 6.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 20 100 93.3 N.A. 26.6 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.3 21.4
Protein Similarity: N.A. N.A. N.A. N.A. 38.3 38.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 70 0 0 0 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 16 8 8 8 8 0 % E
% Phe: 8 0 0 16 0 8 0 0 0 8 0 8 0 16 0 % F
% Gly: 0 0 0 0 0 0 16 16 0 0 8 0 0 0 0 % G
% His: 0 0 0 54 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 62 8 8 0 0 8 0 0 0 % I
% Lys: 8 8 8 0 62 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 62 % L
% Met: 0 0 8 0 0 0 0 0 0 8 62 0 8 0 8 % M
% Asn: 0 62 0 8 8 0 0 0 0 0 0 0 0 0 16 % N
% Pro: 8 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 8 0 0 0 0 62 0 8 0 0 0 % Q
% Arg: 70 16 8 0 0 85 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 8 0 0 0 62 70 0 24 0 8 0 0 % S
% Thr: 0 0 0 0 8 0 8 0 8 0 0 0 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 62 70 8 8 % V
% Trp: 0 8 0 0 16 0 0 0 8 0 0 0 0 62 0 % W
% Tyr: 8 0 0 0 0 8 0 0 0 8 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _