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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLG
All Species:
16.67
Human Site:
T509
Identified Species:
30.56
UniProt:
P54098
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54098
NP_001119603.1
1239
139562
T509
K
V
K
K
E
P
A
T
A
S
K
L
P
I
E
Chimpanzee
Pan troglodytes
XP_523149
1236
139116
T506
K
V
K
K
E
P
A
T
A
S
K
L
P
I
E
Rhesus Macaque
Macaca mulatta
XP_001092360
1228
138042
T498
K
V
K
K
E
P
A
T
A
S
K
L
P
I
D
Dog
Lupus familis
XP_545850
1234
138197
A508
V
K
R
K
E
P
T
A
A
S
K
L
P
I
E
Cat
Felis silvestris
Mouse
Mus musculus
P54099
1239
138880
S491
K
K
V
K
K
P
A
S
A
S
K
L
P
I
E
Rat
Rattus norvegicus
Q9QYV8
1216
136837
S490
K
K
V
K
K
T
A
S
A
S
K
L
P
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92076
647
72836
Frog
Xenopus laevis
Q91684
1200
137225
K482
K
I
S
K
K
Q
K
K
A
N
E
A
A
E
S
Zebra Danio
Brachydanio rerio
XP_001921328
1203
137518
E481
K
K
A
K
Q
E
A
E
A
T
E
A
A
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27607
1145
129809
P467
Q
E
L
K
L
K
Q
P
P
K
R
K
P
L
P
Honey Bee
Apis mellifera
XP_395230
1086
125181
K421
Q
S
L
K
K
N
L
K
N
I
S
Q
I
Q
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15801
1254
143484
P453
R
L
T
K
K
G
V
P
A
K
C
Q
K
L
P
Red Bread Mold
Neurospora crassa
Q9Y767
1456
161685
L490
G
D
V
E
R
P
A
L
N
Q
K
L
P
G
Y
Conservation
Percent
Protein Identity:
100
99.1
96.4
87.8
N.A.
85.4
85.6
N.A.
N.A.
41.6
64.8
67.1
N.A.
42.7
39.7
N.A.
N.A.
Protein Similarity:
100
99.3
97.3
91.1
N.A.
89.5
90.3
N.A.
N.A.
47
77
77.6
N.A.
57.8
57.7
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
73.3
66.6
N.A.
N.A.
0
20
26.6
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
80
N.A.
N.A.
0
46.6
53.3
N.A.
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
21.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
38.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
54
8
70
0
0
16
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
16
% D
% Glu:
0
8
0
8
31
8
0
8
0
0
16
0
0
8
39
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
0
0
8
47
0
% I
% Lys:
54
31
24
85
39
8
8
16
0
16
54
8
8
0
0
% K
% Leu:
0
8
16
0
8
0
8
8
0
0
0
54
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
16
8
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
47
0
16
8
0
0
0
62
0
16
% P
% Gln:
16
0
0
0
8
8
8
0
0
8
0
16
0
8
0
% Q
% Arg:
8
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
16
0
47
8
0
0
0
8
% S
% Thr:
0
0
8
0
0
8
8
24
0
8
0
0
0
0
0
% T
% Val:
8
24
24
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _