KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLG
All Species:
36.67
Human Site:
Y282
Identified Species:
67.22
UniProt:
P54098
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54098
NP_001119603.1
1239
139562
Y282
R
A
H
I
R
E
Q
Y
L
I
Q
G
S
R
M
Chimpanzee
Pan troglodytes
XP_523149
1236
139116
Y279
R
A
H
I
R
E
Q
Y
L
I
Q
G
S
R
M
Rhesus Macaque
Macaca mulatta
XP_001092360
1228
138042
Y271
R
A
H
I
R
E
Q
Y
L
I
Q
G
S
H
M
Dog
Lupus familis
XP_545850
1234
138197
Y281
R
A
H
I
R
E
Q
Y
L
I
Q
G
S
R
M
Cat
Felis silvestris
Mouse
Mus musculus
P54099
1239
138880
Y265
R
A
H
I
R
E
Q
Y
L
I
Q
D
S
R
M
Rat
Rattus norvegicus
Q9QYV8
1216
136837
Y265
R
A
H
I
R
E
Q
Y
L
I
Q
G
S
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92076
647
72836
Frog
Xenopus laevis
Q91684
1200
137225
Y256
R
A
H
I
K
E
Q
Y
L
I
K
G
S
K
T
Zebra Danio
Brachydanio rerio
XP_001921328
1203
137518
Y251
R
A
H
I
K
E
Q
Y
L
L
K
G
S
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27607
1145
129809
E243
R
P
H
Y
T
T
D
E
L
I
P
L
G
T
T
Honey Bee
Apis mellifera
XP_395230
1086
125181
E218
F
D
R
S
K
I
K
E
Q
Y
W
L
K
Q
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15801
1254
143484
Y238
R
A
R
V
L
E
E
Y
N
F
R
D
S
K
A
Red Bread Mold
Neurospora crassa
Q9Y767
1456
161685
Y257
R
A
K
I
L
E
E
Y
D
L
K
Q
T
R
N
Conservation
Percent
Protein Identity:
100
99.1
96.4
87.8
N.A.
85.4
85.6
N.A.
N.A.
41.6
64.8
67.1
N.A.
42.7
39.7
N.A.
N.A.
Protein Similarity:
100
99.3
97.3
91.1
N.A.
89.5
90.3
N.A.
N.A.
47
77
77.6
N.A.
57.8
57.7
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
93.3
100
N.A.
N.A.
0
73.3
73.3
N.A.
26.6
0
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
100
N.A.
N.A.
0
93.3
100
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
21.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
38.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
77
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
8
0
0
16
0
0
0
% D
% Glu:
0
0
0
0
0
77
16
16
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
54
8
0
0
% G
% His:
0
0
70
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
70
0
8
0
0
0
62
0
0
0
0
0
% I
% Lys:
0
0
8
0
24
0
8
0
0
0
24
0
8
24
0
% K
% Leu:
0
0
0
0
16
0
0
0
70
16
0
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
62
0
8
0
47
8
0
8
0
% Q
% Arg:
85
0
16
0
47
0
0
0
0
0
8
0
0
47
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
0
0
70
0
0
% S
% Thr:
0
0
0
0
8
8
0
0
0
0
0
0
8
8
24
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
77
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _