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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLG
All Species:
31.82
Human Site:
Y614
Identified Species:
58.33
UniProt:
P54098
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54098
NP_001119603.1
1239
139562
Y614
W
D
G
F
P
L
H
Y
S
E
R
H
G
W
G
Chimpanzee
Pan troglodytes
XP_523149
1236
139116
Y611
W
D
G
F
P
L
H
Y
S
E
R
H
G
W
G
Rhesus Macaque
Macaca mulatta
XP_001092360
1228
138042
Y603
W
D
G
F
P
L
H
Y
S
E
R
H
G
W
G
Dog
Lupus familis
XP_545850
1234
138197
Y610
W
D
G
F
P
L
H
Y
S
E
R
H
G
W
G
Cat
Felis silvestris
Mouse
Mus musculus
P54099
1239
138880
Y596
W
D
G
F
P
L
H
Y
S
D
S
H
G
W
G
Rat
Rattus norvegicus
Q9QYV8
1216
136837
Y595
W
D
G
F
P
L
H
Y
S
D
S
H
G
W
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92076
647
72836
Y71
H
R
A
I
E
R
L
Y
R
Q
H
C
L
Q
R
Frog
Xenopus laevis
Q91684
1200
137225
Y586
W
D
G
Y
P
L
H
Y
S
E
K
H
G
W
G
Zebra Danio
Brachydanio rerio
XP_001921328
1203
137518
Y582
W
D
G
F
P
L
H
Y
T
D
Q
H
G
W
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27607
1145
129809
P556
S
T
G
M
Q
I
A
P
K
L
L
S
L
C
W
Honey Bee
Apis mellifera
XP_395230
1086
125181
N510
Q
I
V
P
K
L
L
N
L
T
W
E
N
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15801
1254
143484
A591
E
S
E
L
A
H
Q
A
L
Q
I
N
S
S
G
Red Bread Mold
Neurospora crassa
Q9Y767
1456
161685
P617
P
N
A
R
C
V
N
P
M
A
K
G
Y
L
P
Conservation
Percent
Protein Identity:
100
99.1
96.4
87.8
N.A.
85.4
85.6
N.A.
N.A.
41.6
64.8
67.1
N.A.
42.7
39.7
N.A.
N.A.
Protein Similarity:
100
99.3
97.3
91.1
N.A.
89.5
90.3
N.A.
N.A.
47
77
77.6
N.A.
57.8
57.7
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
6.6
86.6
80
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
13.3
100
100
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
21.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
38.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
8
0
8
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
62
0
0
0
0
0
0
0
24
0
0
0
0
0
% D
% Glu:
8
0
8
0
8
0
0
0
0
39
0
8
0
0
0
% E
% Phe:
0
0
0
54
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
70
0
0
0
0
0
0
0
0
8
62
0
70
% G
% His:
8
0
0
0
0
8
62
0
0
0
8
62
0
0
0
% H
% Ile:
0
8
0
8
0
8
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
8
0
16
0
0
0
0
% K
% Leu:
0
0
0
8
0
70
16
0
16
8
8
0
16
8
0
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
8
0
0
0
8
8
0
0
% N
% Pro:
8
0
0
8
62
0
0
16
0
0
0
0
0
0
16
% P
% Gln:
8
0
0
0
8
0
8
0
0
16
8
0
0
8
0
% Q
% Arg:
0
8
0
8
0
8
0
0
8
0
31
0
0
0
8
% R
% Ser:
8
8
0
0
0
0
0
0
54
0
16
8
8
8
0
% S
% Thr:
0
8
0
0
0
0
0
0
8
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
62
0
0
0
0
0
0
0
0
0
8
0
0
62
8
% W
% Tyr:
0
0
0
8
0
0
0
70
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _