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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLG
All Species:
27.58
Human Site:
Y732
Identified Species:
50.56
UniProt:
P54098
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54098
NP_001119603.1
1239
139562
Y732
P
K
D
T
Q
P
S
Y
H
H
G
N
G
P
Y
Chimpanzee
Pan troglodytes
XP_523149
1236
139116
Y729
P
K
D
T
Q
P
S
Y
H
H
G
N
G
P
Y
Rhesus Macaque
Macaca mulatta
XP_001092360
1228
138042
Y721
P
K
D
S
Q
P
N
Y
H
H
G
N
G
P
Y
Dog
Lupus familis
XP_545850
1234
138197
Y733
S
A
L
G
Q
P
A
Y
H
H
G
N
G
P
Y
Cat
Felis silvestris
Mouse
Mus musculus
P54099
1239
138880
Y711
P
K
S
S
Q
P
T
Y
H
H
G
N
G
P
Y
Rat
Rattus norvegicus
Q9QYV8
1216
136837
Y709
P
K
T
S
Q
P
T
Y
H
H
G
N
G
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92076
647
72836
G169
F
K
L
P
H
K
D
G
N
E
N
N
V
G
S
Frog
Xenopus laevis
Q91684
1200
137225
N702
E
F
D
S
L
P
D
N
H
H
G
N
S
P
C
Zebra Danio
Brachydanio rerio
XP_001921328
1203
137518
Y693
S
L
N
G
E
C
P
Y
H
H
G
N
G
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27607
1145
129809
G655
E
T
Q
Y
Q
G
S
G
V
W
C
N
K
V
L
Honey Bee
Apis mellifera
XP_395230
1086
125181
D608
K
G
S
A
H
W
C
D
T
N
I
D
N
C
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15801
1254
143484
S703
S
E
E
L
W
I
A
S
L
V
G
D
S
I
F
Red Bread Mold
Neurospora crassa
Q9Y767
1456
161685
S750
S
E
E
L
W
I
A
S
V
V
G
D
A
T
F
Conservation
Percent
Protein Identity:
100
99.1
96.4
87.8
N.A.
85.4
85.6
N.A.
N.A.
41.6
64.8
67.1
N.A.
42.7
39.7
N.A.
N.A.
Protein Similarity:
100
99.3
97.3
91.1
N.A.
89.5
90.3
N.A.
N.A.
47
77
77.6
N.A.
57.8
57.7
N.A.
N.A.
P-Site Identity:
100
100
86.6
66.6
N.A.
80
80
N.A.
N.A.
13.3
46.6
53.3
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
93.3
N.A.
N.A.
20
53.3
66.6
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
21.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
38.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
24
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
8
0
0
0
8
0
0
8
16
% C
% Asp:
0
0
31
0
0
0
16
8
0
0
0
24
0
0
0
% D
% Glu:
16
16
16
0
8
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
16
% F
% Gly:
0
8
0
16
0
8
0
16
0
0
77
0
54
8
0
% G
% His:
0
0
0
0
16
0
0
0
62
62
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
16
0
0
0
0
8
0
0
8
0
% I
% Lys:
8
47
0
0
0
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
8
16
16
8
0
0
0
8
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
8
8
8
8
77
8
0
0
% N
% Pro:
39
0
0
8
0
54
8
0
0
0
0
0
0
62
0
% P
% Gln:
0
0
8
0
54
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
31
0
16
31
0
0
24
16
0
0
0
0
16
0
8
% S
% Thr:
0
8
8
16
0
0
16
0
8
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
16
16
0
0
8
8
0
% V
% Trp:
0
0
0
0
16
8
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
54
0
0
0
0
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _