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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLG
All Species:
35.15
Human Site:
Y837
Identified Species:
64.44
UniProt:
P54098
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54098
NP_001119603.1
1239
139562
Y837
D
Y
D
E
E
G
L
Y
G
A
I
L
P
Q
V
Chimpanzee
Pan troglodytes
XP_523149
1236
139116
Y834
D
Y
D
E
E
G
L
Y
G
A
I
L
P
Q
V
Rhesus Macaque
Macaca mulatta
XP_001092360
1228
138042
Y826
D
Y
D
E
E
G
L
Y
G
A
I
L
P
Q
V
Dog
Lupus familis
XP_545850
1234
138197
Y838
D
Y
D
E
E
G
R
Y
G
A
I
L
P
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
P54099
1239
138880
Y816
A
F
D
E
E
G
H
Y
G
A
I
L
P
Q
V
Rat
Rattus norvegicus
Q9QYV8
1216
136837
Y814
S
F
D
E
E
S
H
Y
G
A
I
L
P
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92076
647
72836
P269
I
T
R
R
A
V
E
P
T
W
L
T
A
S
N
Frog
Xenopus laevis
Q91684
1200
137225
Y807
E
F
D
E
E
N
K
Y
G
A
I
L
A
Q
V
Zebra Danio
Brachydanio rerio
XP_001921328
1203
137518
Y798
D
Y
D
E
E
G
Q
Y
G
A
I
L
P
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27607
1145
129809
Y755
E
K
C
Q
P
I
A
Y
G
A
I
C
P
Q
V
Honey Bee
Apis mellifera
XP_395230
1086
125181
A708
G
A
I
L
P
L
V
A
V
C
G
T
L
T
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P15801
1254
143484
T836
P
V
L
G
C
G
I
T
Y
S
L
M
K
K
N
Red Bread Mold
Neurospora crassa
Q9Y767
1456
161685
T885
P
V
L
G
A
G
I
T
E
A
L
M
S
R
W
Conservation
Percent
Protein Identity:
100
99.1
96.4
87.8
N.A.
85.4
85.6
N.A.
N.A.
41.6
64.8
67.1
N.A.
42.7
39.7
N.A.
N.A.
Protein Similarity:
100
99.3
97.3
91.1
N.A.
89.5
90.3
N.A.
N.A.
47
77
77.6
N.A.
57.8
57.7
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
73.3
N.A.
N.A.
0
66.6
93.3
N.A.
46.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
N.A.
6.6
80
93.3
N.A.
60
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
21.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.3
38.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
16
0
8
8
0
77
0
0
16
0
0
% A
% Cys:
0
0
8
0
8
0
0
0
0
8
0
8
0
0
0
% C
% Asp:
39
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
0
0
62
62
0
8
0
8
0
0
0
0
0
0
% E
% Phe:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
16
0
62
0
0
70
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
8
16
0
0
0
70
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
8
0
0
0
0
0
8
8
0
% K
% Leu:
0
0
16
8
0
8
24
0
0
0
24
62
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
16
% N
% Pro:
16
0
0
0
16
0
0
8
0
0
0
0
62
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
0
0
0
70
0
% Q
% Arg:
0
0
8
8
0
0
8
0
0
0
0
0
0
8
8
% R
% Ser:
8
0
0
0
0
8
0
0
0
8
0
0
8
8
0
% S
% Thr:
0
8
0
0
0
0
0
16
8
0
0
16
0
8
0
% T
% Val:
0
16
0
0
0
8
8
0
8
0
0
0
0
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% W
% Tyr:
0
39
0
0
0
0
0
70
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _