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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLNS1A
All Species:
5.15
Human Site:
S71
Identified Species:
8.1
UniProt:
P54105
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54105
NP_001284.1
237
26215
S71
H
A
L
S
R
D
R
S
D
C
L
G
E
H
L
Chimpanzee
Pan troglodytes
XP_001175048
222
24569
L63
L
E
Y
P
T
I
S
L
H
A
L
S
R
D
R
Rhesus Macaque
Macaca mulatta
XP_001088333
203
22330
L44
L
Y
I
A
E
S
R
L
S
W
L
D
G
S
G
Dog
Lupus familis
XP_535567
226
24585
R67
R
D
L
N
A
Y
P
R
K
H
L
Y
V
M
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61189
236
26003
N71
H
A
V
S
R
D
P
N
A
Y
P
Q
E
H
L
Rat
Rattus norvegicus
Q04753
236
26074
N71
H
A
V
S
R
D
P
N
A
Y
P
Q
E
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519221
278
30242
T79
T
A
L
G
T
R
F
T
L
N
A
T
P
P
P
Chicken
Gallus gallus
XP_423253
238
26615
N69
H
A
V
S
R
D
L
N
A
Y
P
W
E
H
L
Frog
Xenopus laevis
P54106
241
26428
A69
H
A
I
S
R
D
T
A
A
Y
P
E
E
H
L
Zebra Danio
Brachydanio rerio
NP_571499
249
27316
S69
H
A
I
S
R
D
L
S
A
F
P
E
E
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611237
215
23724
E56
L
A
E
G
I
S
I
E
W
K
Q
V
S
L
H
Honey Bee
Apis mellifera
XP_624081
207
23224
D48
L
L
S
W
V
N
Y
D
T
Q
Q
G
F
S
L
Nematode Worm
Caenorhab. elegans
NP_001021287
205
22895
S46
S
A
V
I
W
I
S
S
A
A
G
T
K
G
F
Sea Urchin
Strong. purpuratus
XP_001194575
165
18108
Poplar Tree
Populus trichocarpa
XP_002318279
231
25740
A71
V
D
G
T
K
G
Y
A
V
D
F
L
S
I
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
85.6
82.2
N.A.
90.3
90.3
N.A.
40.6
82.3
72.1
68.2
N.A.
20.2
40
29.9
24.4
Protein Similarity:
100
93.2
85.6
85.2
N.A.
94.9
94.9
N.A.
53.2
90.3
82.5
80.3
N.A.
37.5
56.5
45.5
40.9
P-Site Identity:
100
6.6
13.3
13.3
N.A.
53.3
53.3
N.A.
13.3
53.3
53.3
60
N.A.
6.6
13.3
13.3
0
P-Site Similarity:
100
6.6
26.6
26.6
N.A.
66.6
66.6
N.A.
20
66.6
66.6
66.6
N.A.
6.6
20
26.6
0
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
7
7
0
0
14
40
14
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
14
0
0
0
40
0
7
7
7
0
7
0
7
0
% D
% Glu:
0
7
7
0
7
0
0
7
0
0
0
14
40
0
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
7
7
0
7
0
7
% F
% Gly:
0
0
7
14
0
7
0
0
0
0
7
14
7
7
7
% G
% His:
40
0
0
0
0
0
0
0
7
7
0
0
0
40
7
% H
% Ile:
0
0
20
7
7
14
7
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
7
0
0
0
7
7
0
0
7
0
0
% K
% Leu:
27
7
20
0
0
0
14
14
7
0
27
7
0
7
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
0
0
7
0
7
0
20
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
20
0
0
0
34
0
7
7
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
14
14
0
0
0
% Q
% Arg:
7
0
0
0
40
7
14
7
0
0
0
0
7
0
7
% R
% Ser:
7
0
7
40
0
14
14
20
7
0
0
7
14
14
7
% S
% Thr:
7
0
0
7
14
0
7
7
7
0
0
14
0
0
0
% T
% Val:
7
0
27
0
7
0
0
0
7
0
0
7
7
0
7
% V
% Trp:
0
0
0
7
7
0
0
0
7
7
0
7
0
0
0
% W
% Tyr:
0
7
7
0
0
7
14
0
0
27
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _