Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRISP3 All Species: 13.33
Human Site: T222 Identified Species: 32.59
UniProt: P54108 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54108 NP_006052.1 245 27630 T222 N C K S L K L T L T C K H Q L
Chimpanzee Pan troglodytes XP_001148602 258 29058 T235 N C K S L K L T L T C K H Q L
Rhesus Macaque Macaca mulatta Q9XSD3 249 28634 F226 D C S L E V R F L G C N H S T
Dog Lupus familis XP_532166 246 27500 T223 N C D S L K K T A G C E H E L
Cat Felis silvestris
Mouse Mus musculus P16563 243 27587 S220 N C E S L K T S A G C K H E L
Rat Rattus norvegicus P12020 246 27829 M223 N C G D L K K M V S C D D P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509451 233 26465 N210 N C P D L A K N P G C D D E N
Chicken Gallus gallus XP_420051 170 18975 G148 W Y N S Y Q V G C A V A Y C P
Frog Xenopus laevis NP_001082594 241 26932 Y218 G C S N F I A Y C N I I P M I
Zebra Danio Brachydanio rerio XP_001922209 223 24196 T201 A K L T C E N T A V K L G C P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 44.5 69.1 N.A. 59.1 54.8 N.A. 49.7 41.2 40.8 42 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 94.5 59 82.9 N.A. 75 69.1 N.A. 63.2 49.3 58.3 55.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 26.6 60 N.A. 60 40 N.A. 26.6 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 73.3 N.A. 80 53.3 N.A. 33.3 26.6 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 10 0 30 10 0 10 0 0 0 % A
% Cys: 0 80 0 0 10 0 0 0 20 0 70 0 0 20 0 % C
% Asp: 10 0 10 20 0 0 0 0 0 0 0 20 20 0 0 % D
% Glu: 0 0 10 0 10 10 0 0 0 0 0 10 0 30 0 % E
% Phe: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 0 0 0 10 0 40 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 10 10 0 0 10 % I
% Lys: 0 10 20 0 0 50 30 0 0 0 10 30 0 0 0 % K
% Leu: 0 0 10 10 60 0 20 0 30 0 0 10 0 0 50 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % M
% Asn: 60 0 10 10 0 0 10 10 0 10 0 10 0 0 10 % N
% Pro: 0 0 10 0 0 0 0 0 10 0 0 0 10 10 20 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 20 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 20 50 0 0 0 10 0 10 0 0 0 10 0 % S
% Thr: 0 0 0 10 0 0 10 40 0 20 0 0 0 0 10 % T
% Val: 0 0 0 0 0 10 10 0 10 10 10 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 10 0 0 10 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _