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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRISP3
All Species:
4.55
Human Site:
Y120
Identified Species:
11.11
UniProt:
P54108
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54108
NP_006052.1
245
27630
Y120
I
Q
S
W
F
D
E
Y
N
D
F
D
F
G
V
Chimpanzee
Pan troglodytes
XP_001148602
258
29058
Y133
I
Q
S
W
F
D
E
Y
N
D
F
D
F
G
V
Rhesus Macaque
Macaca mulatta
Q9XSD3
249
28634
K124
G
V
W
Y
S
E
S
K
Y
F
R
Y
G
L
W
Dog
Lupus familis
XP_532166
246
27500
R121
I
Q
N
W
Y
E
E
R
H
N
F
V
Y
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P16563
243
27587
E118
V
I
Q
S
W
Y
N
E
N
E
D
F
V
Y
G
Rat
Rattus norvegicus
P12020
246
27829
E121
V
I
Q
D
W
Y
D
E
S
L
D
F
V
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509451
233
26465
E108
A
I
Q
A
F
Y
D
E
V
Q
D
F
K
Y
G
Chicken
Gallus gallus
XP_420051
170
18975
L46
I
V
D
K
H
N
A
L
R
R
R
V
S
P
P
Frog
Xenopus laevis
NP_001082594
241
26932
G116
I
Q
A
W
Y
S
E
G
E
F
F
N
M
E
W
Zebra Danio
Brachydanio rerio
XP_001922209
223
24196
E99
V
V
D
A
W
H
S
E
V
N
N
Y
K
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
44.5
69.1
N.A.
59.1
54.8
N.A.
49.7
41.2
40.8
42
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.5
59
82.9
N.A.
75
69.1
N.A.
63.2
49.3
58.3
55.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
46.6
N.A.
6.6
0
N.A.
6.6
6.6
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
86.6
N.A.
26.6
26.6
N.A.
13.3
13.3
53.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
20
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
10
0
20
20
0
0
20
30
20
0
0
0
% D
% Glu:
0
0
0
0
0
20
40
40
10
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
30
0
0
0
0
20
40
30
20
10
0
% F
% Gly:
10
0
0
0
0
0
0
10
0
0
0
0
10
30
30
% G
% His:
0
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% H
% Ile:
50
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
10
0
0
0
0
20
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
10
0
0
10
10
0
30
20
10
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
20
% P
% Gln:
0
40
30
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
10
20
0
0
0
0
% R
% Ser:
0
0
20
10
10
10
20
0
10
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
30
30
0
0
0
0
0
0
20
0
0
20
20
0
30
% V
% Trp:
0
0
10
40
30
0
0
0
0
0
0
0
0
0
20
% W
% Tyr:
0
0
0
10
20
30
0
20
10
0
0
20
10
30
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _