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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLM All Species: 7.27
Human Site: S212 Identified Species: 12.31
UniProt: P54132 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54132 NP_000048.1 1417 159000 S212 K T D L P P P S S E S E Q I D
Chimpanzee Pan troglodytes XP_510594 1417 158822 S212 K T D L P P P S S E T E Q I D
Rhesus Macaque Macaca mulatta XP_001097543 1416 158885 F212 K A D L P P S F S E S E Q I D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88700 1416 158347 L212 T P P S P E C L Q V D L T K E
Rat Rattus norvegicus Q6AYJ1 621 69624
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515695 791 89186
Chicken Gallus gallus Q9I920 1142 126164 E15 D V V P P S P E E E L P S F S
Frog Xenopus laevis Q9DEY9 1364 152305 Y201 H D C A K L L Y D N N E V A S
Zebra Danio Brachydanio rerio XP_701357 1261 139417 K134 P K S A A L P K D S T N D Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 G295 S P E K S G S G E Q G Y K L G
Honey Bee Apis mellifera XP_396209 961 109321
Nematode Worm Caenorhab. elegans O18017 988 110641
Sea Urchin Strong. purpuratus XP_001175892 1394 152920 K222 G S A K K S Q K N R A V I L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35187 1447 163819 S209 I I E S T S L S E D A K R L Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.1 N.A. N.A. 76.9 21.2 N.A. 46.3 47.9 50.8 41.6 N.A. 27.8 30.9 26.5 31.5
Protein Similarity: 100 99.2 97.7 N.A. N.A. 85.2 30.9 N.A. 50.1 60.7 66.6 54 N.A. 47 47.1 40.2 47.6
P-Site Identity: 100 93.3 80 N.A. N.A. 6.6 0 N.A. 0 20 6.6 6.6 N.A. 0 0 0 6.6
P-Site Similarity: 100 100 80 N.A. N.A. 13.3 0 N.A. 0 20 13.3 13.3 N.A. 26.6 0 0 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 15 8 0 0 0 0 0 15 0 0 8 0 % A
% Cys: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 22 0 0 0 0 0 15 8 8 0 8 0 29 % D
% Glu: 0 0 15 0 0 8 0 8 22 29 0 29 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % F
% Gly: 8 0 0 0 0 8 0 8 0 0 8 0 0 0 8 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 0 0 0 0 8 22 0 % I
% Lys: 22 8 0 15 15 0 0 15 0 0 0 8 8 8 0 % K
% Leu: 0 0 0 22 0 15 15 8 0 0 8 8 0 22 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 8 8 8 0 0 0 % N
% Pro: 8 15 8 8 36 22 29 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 8 8 0 0 22 8 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % R
% Ser: 8 8 8 15 8 22 15 22 22 8 15 0 8 0 15 % S
% Thr: 8 15 0 0 8 0 0 0 0 0 15 0 8 0 8 % T
% Val: 0 8 8 0 0 0 0 0 0 8 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _