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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLM All Species: 15.45
Human Site: S304 Identified Species: 26.15
UniProt: P54132 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54132 NP_000048.1 1417 159000 S304 D T D F V P P S P E E I I S A
Chimpanzee Pan troglodytes XP_510594 1417 158822 S304 D T D F V P P S P E K I I S S
Rhesus Macaque Macaca mulatta XP_001097543 1416 158885 S304 D I D F V P P S P E E I S A S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88700 1416 158347 S309 D I D F V P P S P E E I I S T
Rat Rattus norvegicus Q6AYJ1 621 69624
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515695 791 89186
Chicken Gallus gallus Q9I920 1142 126164 S100 I P L H E L T S I S C A K E L
Frog Xenopus laevis Q9DEY9 1364 152305 S287 P S D E S L S S P P V L K V I
Zebra Danio Brachydanio rerio XP_701357 1261 139417 L219 I T A P K D V L S A A N G V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 L391 L M E K Y C S L I D Q I P A M
Honey Bee Apis mellifera XP_396209 961 109321
Nematode Worm Caenorhab. elegans O18017 988 110641
Sea Urchin Strong. purpuratus XP_001175892 1394 152920 I317 P T D F N I D I Q W D S F T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35187 1447 163819 T294 S T T A T T V T K A L A I T G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.1 N.A. N.A. 76.9 21.2 N.A. 46.3 47.9 50.8 41.6 N.A. 27.8 30.9 26.5 31.5
Protein Similarity: 100 99.2 97.7 N.A. N.A. 85.2 30.9 N.A. 50.1 60.7 66.6 54 N.A. 47 47.1 40.2 47.6
P-Site Identity: 100 86.6 73.3 N.A. N.A. 86.6 0 N.A. 0 6.6 20 6.6 N.A. 6.6 0 0 20
P-Site Similarity: 100 100 86.6 N.A. N.A. 86.6 0 N.A. 0 6.6 33.3 13.3 N.A. 33.3 0 0 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 0 0 0 15 8 15 0 15 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % C
% Asp: 29 0 43 0 0 8 8 0 0 8 8 0 0 0 0 % D
% Glu: 0 0 8 8 8 0 0 0 0 29 22 0 0 8 0 % E
% Phe: 0 0 0 36 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 15 0 0 0 8 0 8 15 0 0 36 29 0 8 % I
% Lys: 0 0 0 8 8 0 0 0 8 0 8 0 15 0 0 % K
% Leu: 8 0 8 0 0 15 0 15 0 0 8 8 0 0 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 15 8 0 8 0 29 29 0 36 8 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 8 0 0 8 0 15 43 8 8 0 8 8 22 29 % S
% Thr: 0 36 8 0 8 8 8 8 0 0 0 0 0 15 8 % T
% Val: 0 0 0 0 29 0 15 0 0 0 8 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _