KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BLM
All Species:
12.12
Human Site:
S419
Identified Species:
20.51
UniProt:
P54132
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54132
NP_000048.1
1417
159000
S419
T
E
V
D
F
N
K
S
D
A
S
L
L
G
S
Chimpanzee
Pan troglodytes
XP_510594
1417
158822
S419
T
E
V
D
F
N
K
S
D
A
S
L
L
G
S
Rhesus Macaque
Macaca mulatta
XP_001097543
1416
158885
S418
T
E
V
D
F
N
K
S
D
A
S
L
L
G
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88700
1416
158347
N424
A
E
A
G
F
N
G
N
D
V
R
L
L
G
S
Rat
Rattus norvegicus
Q6AYJ1
621
69624
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515695
791
89186
Chicken
Gallus gallus
Q9I920
1142
126164
S200
D
K
L
D
T
S
Y
S
S
K
E
T
D
Q
E
Frog
Xenopus laevis
Q9DEY9
1364
152305
T389
S
S
P
A
D
S
S
T
V
S
L
T
S
C
T
Zebra Danio
Brachydanio rerio
XP_701357
1261
139417
E319
P
P
S
P
I
P
E
E
I
S
L
S
V
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
D497
N
R
N
Q
L
I
H
D
L
C
G
E
P
D
N
Honey Bee
Apis mellifera
XP_396209
961
109321
N19
N
L
L
N
E
S
L
N
C
I
S
K
D
C
K
Nematode Worm
Caenorhab. elegans
O18017
988
110641
C46
G
S
I
R
D
P
S
C
E
E
R
E
E
E
Y
Sea Urchin
Strong. purpuratus
XP_001175892
1394
152920
M423
L
K
P
L
T
A
Q
M
N
A
D
E
L
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35187
1447
163819
F440
E
L
L
N
Q
S
D
F
D
F
V
V
N
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
N.A.
N.A.
76.9
21.2
N.A.
46.3
47.9
50.8
41.6
N.A.
27.8
30.9
26.5
31.5
Protein Similarity:
100
99.2
97.7
N.A.
N.A.
85.2
30.9
N.A.
50.1
60.7
66.6
54
N.A.
47
47.1
40.2
47.6
P-Site Identity:
100
100
100
N.A.
N.A.
53.3
0
N.A.
0
13.3
0
0
N.A.
0
6.6
0
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
60
0
N.A.
0
33.3
33.3
20
N.A.
6.6
33.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
8
0
0
0
29
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
8
0
0
0
15
0
% C
% Asp:
8
0
0
29
15
0
8
8
36
0
8
0
15
15
15
% D
% Glu:
8
29
0
0
8
0
8
8
8
8
8
22
8
8
15
% E
% Phe:
0
0
0
0
29
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
8
0
0
0
8
0
0
29
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
8
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
15
0
0
0
0
22
0
0
8
0
8
0
0
8
% K
% Leu:
8
15
22
8
8
0
8
0
8
0
15
29
36
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
15
0
8
15
0
29
0
15
8
0
0
0
8
0
8
% N
% Pro:
8
8
15
8
0
15
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
8
8
0
8
0
0
0
0
0
0
15
0
% Q
% Arg:
0
8
0
8
0
0
0
0
0
0
15
0
0
0
0
% R
% Ser:
8
15
8
0
0
29
15
29
8
15
29
8
8
8
29
% S
% Thr:
22
0
0
0
15
0
0
8
0
0
0
15
0
0
8
% T
% Val:
0
0
22
0
0
0
0
0
8
8
8
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _