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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BLM
All Species:
11.82
Human Site:
S464
Identified Species:
20
UniProt:
P54132
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54132
NP_000048.1
1417
159000
S464
H
L
P
S
N
S
V
S
P
G
D
C
L
L
T
Chimpanzee
Pan troglodytes
XP_510594
1417
158822
S464
H
L
P
S
N
S
V
S
P
G
D
C
L
L
T
Rhesus Macaque
Macaca mulatta
XP_001097543
1416
158885
S463
H
L
P
S
N
S
V
S
P
G
D
Y
L
L
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88700
1416
158347
S469
Y
L
L
S
H
S
P
S
T
E
E
C
L
P
T
Rat
Rattus norvegicus
Q6AYJ1
621
69624
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515695
791
89186
Chicken
Gallus gallus
Q9I920
1142
126164
P245
N
G
S
W
C
E
K
P
T
G
K
D
S
G
N
Frog
Xenopus laevis
Q9DEY9
1364
152305
I434
N
K
L
A
V
H
D
I
G
T
K
E
S
E
N
Zebra Danio
Brachydanio rerio
XP_701357
1261
139417
A364
S
A
K
G
L
K
G
A
D
D
A
L
F
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
D542
S
P
P
S
K
Q
N
D
P
H
L
L
R
K
C
Honey Bee
Apis mellifera
XP_396209
961
109321
D64
K
S
N
V
K
E
K
D
Y
K
S
S
L
D
N
Nematode Worm
Caenorhab. elegans
O18017
988
110641
P91
R
Y
R
P
S
E
N
P
G
P
S
S
S
S
Y
Sea Urchin
Strong. purpuratus
XP_001175892
1394
152920
P468
T
K
D
L
V
P
P
P
Q
L
A
T
L
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35187
1447
163819
K485
T
I
T
L
S
Q
N
K
N
V
Q
V
I
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
N.A.
N.A.
76.9
21.2
N.A.
46.3
47.9
50.8
41.6
N.A.
27.8
30.9
26.5
31.5
Protein Similarity:
100
99.2
97.7
N.A.
N.A.
85.2
30.9
N.A.
50.1
60.7
66.6
54
N.A.
47
47.1
40.2
47.6
P-Site Identity:
100
100
93.3
N.A.
N.A.
46.6
0
N.A.
0
6.6
0
0
N.A.
20
6.6
0
6.6
P-Site Similarity:
100
100
93.3
N.A.
N.A.
66.6
0
N.A.
0
13.3
13.3
6.6
N.A.
20
6.6
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
8
0
0
15
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
22
0
0
8
% C
% Asp:
0
0
8
0
0
0
8
15
8
8
22
8
0
8
0
% D
% Glu:
0
0
0
0
0
22
0
0
0
8
8
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
8
0
0
8
0
15
29
0
0
0
8
0
% G
% His:
22
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
8
15
8
0
15
8
15
8
0
8
15
0
0
15
0
% K
% Leu:
0
29
15
15
8
0
0
0
0
8
8
15
43
29
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
8
0
22
0
22
0
8
0
0
0
0
0
22
% N
% Pro:
0
8
29
8
0
8
15
22
29
8
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
15
0
0
8
0
8
0
0
0
8
% Q
% Arg:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
15
8
8
36
15
29
0
29
0
0
15
15
22
15
8
% S
% Thr:
15
0
8
0
0
0
0
0
15
8
0
8
0
0
29
% T
% Val:
0
0
0
8
15
0
22
0
0
8
0
8
0
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
8
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _