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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BLM
All Species:
17.58
Human Site:
S754
Identified Species:
29.74
UniProt:
P54132
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54132
NP_000048.1
1417
159000
S754
T
N
I
Y
L
Q
L
S
K
K
D
P
I
I
K
Chimpanzee
Pan troglodytes
XP_510594
1417
158822
S754
T
N
I
Y
L
Q
L
S
K
K
D
P
I
I
K
Rhesus Macaque
Macaca mulatta
XP_001097543
1416
158885
S753
T
N
I
Y
L
Q
L
S
K
K
D
P
I
I
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88700
1416
158347
S762
A
N
I
Y
L
Q
L
S
K
K
D
P
I
I
K
Rat
Rattus norvegicus
Q6AYJ1
621
69624
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515695
791
89186
E164
L
A
R
F
V
I
D
E
A
H
C
V
S
Q
W
Chicken
Gallus gallus
Q9I920
1142
126164
D515
S
A
L
E
N
L
Y
D
R
K
L
L
A
R
F
Frog
Xenopus laevis
Q9DEY9
1364
152305
S706
A
S
I
Y
L
Q
L
S
K
K
D
P
I
I
K
Zebra Danio
Brachydanio rerio
XP_701357
1261
139417
A634
R
K
T
F
T
P
P
A
P
K
S
I
K
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
E824
M
A
I
Y
R
D
L
E
S
Q
P
P
M
V
K
Honey Bee
Apis mellifera
XP_396209
961
109321
E334
E
S
Y
I
K
K
K
E
D
I
D
S
H
I
S
Nematode Worm
Caenorhab. elegans
O18017
988
110641
F361
G
R
L
N
S
V
F
F
D
L
H
R
R
G
L
Sea Urchin
Strong. purpuratus
XP_001175892
1394
152920
V757
S
E
M
P
P
E
V
V
S
D
N
P
F
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35187
1447
163819
F765
A
E
Q
R
R
Q
T
F
N
L
F
I
N
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
N.A.
N.A.
76.9
21.2
N.A.
46.3
47.9
50.8
41.6
N.A.
27.8
30.9
26.5
31.5
Protein Similarity:
100
99.2
97.7
N.A.
N.A.
85.2
30.9
N.A.
50.1
60.7
66.6
54
N.A.
47
47.1
40.2
47.6
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
0
N.A.
0
6.6
86.6
6.6
N.A.
33.3
13.3
0
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
0
N.A.
13.3
26.6
93.3
20
N.A.
53.3
26.6
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
22
0
0
0
0
0
8
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
8
15
8
43
0
0
0
0
% D
% Glu:
8
15
0
8
0
8
0
22
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
15
0
0
8
15
0
0
8
0
8
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% H
% Ile:
0
0
43
8
0
8
0
0
0
8
0
15
36
43
0
% I
% Lys:
0
8
0
0
8
8
8
0
36
50
0
0
8
0
43
% K
% Leu:
8
0
15
0
36
8
43
0
0
15
8
8
0
0
15
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
29
0
8
8
0
0
0
8
0
8
0
8
0
0
% N
% Pro:
0
0
0
8
8
8
8
0
8
0
8
50
0
0
8
% P
% Gln:
0
0
8
0
0
43
0
0
0
8
0
0
0
8
0
% Q
% Arg:
8
8
8
8
15
0
0
0
8
0
0
8
8
8
0
% R
% Ser:
15
15
0
0
8
0
0
36
15
0
8
8
8
8
8
% S
% Thr:
22
0
8
0
8
0
8
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
8
8
8
8
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
8
43
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _