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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLM All Species: 17.27
Human Site: S923 Identified Species: 29.23
UniProt: P54132 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54132 NP_000048.1 1417 159000 S923 L A Y H A G L S D S A R D E V
Chimpanzee Pan troglodytes XP_510594 1417 158822 S923 L A Y H A G L S D S A R D E V
Rhesus Macaque Macaca mulatta XP_001097543 1416 158885 S922 L A Y H A G L S D S A R D E V
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88700 1416 158347 S931 L A Y H A G L S D S A R D E V
Rat Rattus norvegicus Q6AYJ1 621 69624 Q153 D Q L M V L Q Q L G I S A T M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515695 791 89186 K323 A F G M G I D K P D V R Y V I
Chicken Gallus gallus Q9I920 1142 126164 C674 Q E G C Q V I C A T I A F G M
Frog Xenopus laevis Q9DEY9 1364 152305 A875 L A Y H A G L A D S N R D Y V
Zebra Danio Brachydanio rerio XP_701357 1261 139417 N793 R M I S A L Q N L Y E R G L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 T993 V S Y H A G L T D T D R E S R
Honey Bee Apis mellifera XP_396209 961 109321 L493 K D P A L K L L Y V T P E K I
Nematode Worm Caenorhab. elegans O18017 988 110641 F520 R S W I A N K F D V I C A T I
Sea Urchin Strong. purpuratus XP_001175892 1394 152920 C917 F V I D E A H C V S Q W G H D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35187 1447 163819 E935 A Y Y H A G M E P D E R L S V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.1 N.A. N.A. 76.9 21.2 N.A. 46.3 47.9 50.8 41.6 N.A. 27.8 30.9 26.5 31.5
Protein Similarity: 100 99.2 97.7 N.A. N.A. 85.2 30.9 N.A. 50.1 60.7 66.6 54 N.A. 47 47.1 40.2 47.6
P-Site Identity: 100 100 100 N.A. N.A. 100 0 N.A. 6.6 0 80 13.3 N.A. 46.6 6.6 13.3 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 6.6 N.A. 13.3 20 86.6 26.6 N.A. 80 26.6 33.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 36 0 8 65 8 0 8 8 0 29 8 15 0 0 % A
% Cys: 0 0 0 8 0 0 0 15 0 0 0 8 0 0 0 % C
% Asp: 8 8 0 8 0 0 8 0 50 15 8 0 36 0 8 % D
% Glu: 0 8 0 0 8 0 0 8 0 0 15 0 15 29 0 % E
% Phe: 8 8 0 0 0 0 0 8 0 0 0 0 8 0 0 % F
% Gly: 0 0 15 0 8 50 0 0 0 8 0 0 15 8 0 % G
% His: 0 0 0 50 0 0 8 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 15 8 0 8 8 0 0 0 22 0 0 0 22 % I
% Lys: 8 0 0 0 0 8 8 8 0 0 0 0 0 8 0 % K
% Leu: 36 0 8 0 8 15 50 8 15 0 0 0 8 8 8 % L
% Met: 0 8 0 15 0 0 8 0 0 0 0 0 0 0 15 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 8 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 15 0 0 8 0 0 0 % P
% Gln: 8 8 0 0 8 0 15 8 0 0 8 0 0 0 0 % Q
% Arg: 15 0 0 0 0 0 0 0 0 0 0 65 0 0 8 % R
% Ser: 0 15 0 8 0 0 0 29 0 43 0 8 0 15 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 15 8 0 0 15 0 % T
% Val: 8 8 0 0 8 8 0 0 8 15 8 0 0 8 43 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 8 50 0 0 0 0 0 8 8 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _