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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLM All Species: 19.09
Human Site: Y784 Identified Species: 32.31
UniProt: P54132 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54132 NP_000048.1 1417 159000 Y784 I S T L E N L Y E R K L L A R
Chimpanzee Pan troglodytes XP_510594 1417 158822 Y784 I S T L E N L Y E R K L L A R
Rhesus Macaque Macaca mulatta XP_001097543 1416 158885 Y783 I S T L E N L Y E R K L L A R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88700 1416 158347 Y792 I S T L E N L Y E R K L L A R
Rat Rattus norvegicus Q6AYJ1 621 69624 Q24 E L H A V D I Q I Q E L T E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515695 791 89186 V194 Q K F P S V P V M A L T A T A
Chicken Gallus gallus Q9I920 1142 126164 N545 R K D Y K R L N M L R K K F H
Frog Xenopus laevis Q9DEY9 1364 152305 Y736 I S T M E N L Y E R Q L L A R
Zebra Danio Brachydanio rerio XP_701357 1261 139417 P664 G F N F P H S P E M M K I F H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 N854 Q D T L D T L N S N N Y I S R
Honey Bee Apis mellifera XP_396209 961 109321 I364 I F Q L K K P I K A S V T S E
Nematode Worm Caenorhab. elegans O18017 988 110641 Y391 G H D F R P D Y T K L S S L R
Sea Urchin Strong. purpuratus XP_001175892 1394 152920 R787 T F G L H Q F R E N Q L E A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35187 1447 163819 R795 Q C K R A I S R L Y A D G K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.1 N.A. N.A. 76.9 21.2 N.A. 46.3 47.9 50.8 41.6 N.A. 27.8 30.9 26.5 31.5
Protein Similarity: 100 99.2 97.7 N.A. N.A. 85.2 30.9 N.A. 50.1 60.7 66.6 54 N.A. 47 47.1 40.2 47.6
P-Site Identity: 100 100 100 N.A. N.A. 100 13.3 N.A. 0 6.6 86.6 6.6 N.A. 26.6 13.3 13.3 26.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 40 N.A. 0 20 100 20 N.A. 46.6 40 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 0 0 0 15 8 0 8 43 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 15 0 8 8 8 0 0 0 0 8 0 0 0 % D
% Glu: 8 0 0 0 36 0 0 0 50 0 8 0 8 8 8 % E
% Phe: 0 22 8 15 0 0 8 0 0 0 0 0 0 15 0 % F
% Gly: 15 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % G
% His: 0 8 8 0 8 8 0 0 0 0 0 0 0 0 15 % H
% Ile: 43 0 0 0 0 8 8 8 8 0 0 0 15 0 8 % I
% Lys: 0 15 8 0 15 8 0 0 8 8 29 15 8 8 0 % K
% Leu: 0 8 0 50 0 0 50 0 8 8 15 50 36 8 8 % L
% Met: 0 0 0 8 0 0 0 0 15 8 8 0 0 0 0 % M
% Asn: 0 0 8 0 0 36 0 15 0 15 8 0 0 0 0 % N
% Pro: 0 0 0 8 8 8 15 8 0 0 0 0 0 0 0 % P
% Gln: 22 0 8 0 0 8 0 8 0 8 15 0 0 0 0 % Q
% Arg: 8 0 0 8 8 8 0 15 0 36 8 0 0 0 58 % R
% Ser: 0 36 0 0 8 0 15 0 8 0 8 8 8 15 0 % S
% Thr: 8 0 43 0 0 8 0 0 8 0 0 8 15 8 0 % T
% Val: 0 0 0 0 8 8 0 8 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 43 0 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _